<p>C, untreated control; *, cancer cell lines carrying <i>TP53</i> mutation. Het, heterozygous TP53 mutation; hom, homozygous <i>TP53</i> mutation.</p
<p>(A) Effect of nutlin-3 on NF-κB luciferase activity. After transfection of vectors or cotransfect...
Aim: The purpose of this manuscript is to study the potential characteristics of acquired nutlin-3 r...
<p>(A–B) Flow cytometry analysis of NIH or NIHLT populations treated with nutlin-3 (5 µM) demonstrat...
Epithelial ovarian cancer is a diverse molecular and clinical disease, yet standard treatment is the...
Epithelial ovarian cancer is a diverse molecular and clinical disease, yet standard treatment is the...
<p><b>A</b>) HCT116 diploid clones D3 and D8, and HCT116 that express wild-type p53 (p53+/+) or are ...
AbstractEvolutionary Action analyses of The Cancer Gene Atlas data sets show that many specific p53 ...
Evolutionary Action analyses of The Cancer Gene Atlas data sets show that many specific p53 missense...
<p>OCI-AML3 cells were treated with Nutlin 3a for indicated time and Western blots done for p53, LC3...
<p>A, H1299 cells transfected with either p53 alone or p53 and indicated HDM2 variants. P53 function...
Six p53 wild-type cancer cell lines from infrequently p53-mutated entities (neuroblastoma, rhabdomyo...
<p>List of genes significantly up-regulated in Nutlin-3a resistant cancer cell lines with wild-type ...
<p>(A) Immunoblot for p53 and p21 from primary caPSCs treated with Nutlin-3a (+) or its inactive ena...
<p>All 15 cell lines were plated at a density of 1 × 10<sup>3</sup> cells per well in 96-well plates...
Wild-type p53 is a stress-responsive tumor suppressor and potent growth inhibitor. Genotoxic stresse...
<p>(A) Effect of nutlin-3 on NF-κB luciferase activity. After transfection of vectors or cotransfect...
Aim: The purpose of this manuscript is to study the potential characteristics of acquired nutlin-3 r...
<p>(A–B) Flow cytometry analysis of NIH or NIHLT populations treated with nutlin-3 (5 µM) demonstrat...
Epithelial ovarian cancer is a diverse molecular and clinical disease, yet standard treatment is the...
Epithelial ovarian cancer is a diverse molecular and clinical disease, yet standard treatment is the...
<p><b>A</b>) HCT116 diploid clones D3 and D8, and HCT116 that express wild-type p53 (p53+/+) or are ...
AbstractEvolutionary Action analyses of The Cancer Gene Atlas data sets show that many specific p53 ...
Evolutionary Action analyses of The Cancer Gene Atlas data sets show that many specific p53 missense...
<p>OCI-AML3 cells were treated with Nutlin 3a for indicated time and Western blots done for p53, LC3...
<p>A, H1299 cells transfected with either p53 alone or p53 and indicated HDM2 variants. P53 function...
Six p53 wild-type cancer cell lines from infrequently p53-mutated entities (neuroblastoma, rhabdomyo...
<p>List of genes significantly up-regulated in Nutlin-3a resistant cancer cell lines with wild-type ...
<p>(A) Immunoblot for p53 and p21 from primary caPSCs treated with Nutlin-3a (+) or its inactive ena...
<p>All 15 cell lines were plated at a density of 1 × 10<sup>3</sup> cells per well in 96-well plates...
Wild-type p53 is a stress-responsive tumor suppressor and potent growth inhibitor. Genotoxic stresse...
<p>(A) Effect of nutlin-3 on NF-κB luciferase activity. After transfection of vectors or cotransfect...
Aim: The purpose of this manuscript is to study the potential characteristics of acquired nutlin-3 r...
<p>(A–B) Flow cytometry analysis of NIH or NIHLT populations treated with nutlin-3 (5 µM) demonstrat...