Total Synthesis of (−)‑<i>N</i>‑Methylwelwitindolinone C Isothiocyanate Based on a Pd-Catalyzed Tandem Enolate Coupling Strategy

The highly stereocontrolled total synthesis of (−)-<i>N</i>-methylwelwitindolinone C isothiocyanate is described, which features the expeditious construction of a bicyclo[4.3.1]­decane ring system by a palladium-catalyzed tandem enolate allylation/arylation reaction