Effects of short-term depletion treatments on bone marrow and splenic T cells.

<p>Percentage of remaining CD3⁺ T cells, CD4⁺ T-helper cells, and CD8⁺ T-cytotoxic cells after one week of treatment in ratio to the mean of control in (<b>A)</b> the bone marrow, and (<b>B)</b> spleen. Values are mean±SEM; ns, non-significant, P>0.05, *<i>P</i><0.05, **<i>P</i><0.01, ***<i>P</i><0.001, post-hoc test (<i>n</i> = 5–6 mice per group). Abbreviations: Bz, bortezomib; CD20, anti-mouse CD20 antibody; Int, Integrin blocking antibodies, anti-LFA1 and anti-VLA4 antibodies.