Persistence of <i>P</i>. <i>aeruginosa</i> AES-1R, AES-1M and PA14, PA14<i>hmgA</i>, in a C57BL/6 mouse model.

<p><b>A</b>. Mice were infected with 10⁶ CFU of AES-1R and AES-1M and lungs examined at 3-hrs and 24-hrs and 72hrs post-infection for bacterial load (latter not shown). <b>B.</b> Mice were infected with 10⁶ CFU wildtype PA14 and PA14<i>hmgA</i> and lungs were examined at 3-hrs, 24-hrs, and 72-hrs post-infection for bacterial load. AES-1M was recovered at significantly higher level compared to AES-1R at 24-hr. PA14Δ<i>hmgA</i> was recovered at a significantly higher level compared to the wild type PA14 at 24- and 72-hrs post-infection. The significances of differences between strains were determined by ANOVA. 4A: *p<0.001vs AES-1R; 4B* p<0.0001 vs. PA14 WT.