<p>B6, Mir155<sup>-/-</sup>, Il10<sup>-/-</sup> and DKO mice were infected with <i>B</i>. <i>burgdorferi</i> and host defense was assessed. <b>A,</b> joints were collected from mice infected for 4 weeks, and ankle skin and hearts were collected from mice infected for 3 weeks, and bacterial numbers were determined by measuring expression of <i>B</i>. <i>burgdorferi 16S rRNA</i>, compared to <i>β-actin</i>. <b>B,</b><i>B</i>. <i>burgdorferi-</i>specific IgG (total), IgG1, IgG2c, and IgG3 were measured by ELISA in serum from mice infected for 4 weeks. Statistically significant differences between strains were determined by ANOVA (Tukey’s post-hoc), and are indicated (* p<0.05), with adjusted p-values included for trends not achieving statistic...
<p><b>A.)</b> Representative immunoblots with sera of mice infected with <i>B</i>. <i>afzelii</i> st...
<p>BMDM from wild type and TLR2 deficient mice were stimulated with <i>B. burgdorferi</i> (MOI 10) f...
a<p>Mouse infection was determined 3 weeks post inoculation by serological response to <i>B. burgdor...
<p>Cytokines were measured by ELISA in serum collected from B6, Mir155<sup>-/-</sup>, Il10<sup>-/-</...
<p>Bone marrow-derived macrophages (BMDMs) and peritoneal macrophages were isolated from B6, Mir155<...
<p>(A) RNA was isolated from <i>B. burgdorferi</i>-infected rear ankle joints at 2 and 4 weeks post-...
<p>(A) Analysis of cytokine secretion of <i>B. burgdorferi</i>-treated BMDMs. Bone marrow-derived ma...
<p>List of 8 most highly differentially expressed miRNAs in <i>B. burgdorferi</i>-infected joints of...
<p><b>A</b>) BMDM from wild type (B6) and Nod2 deficient mice were stimulated with <i>B. burgdorferi...
<p>(A) Representative flow cytometry analysis of CD11b+ cells released from joint tissue of B6 or B6...
<p>Arthritis severity was determined for <i>B. burgdorferi</i>-infected B6 or B6 miR-146a<sup>−/−</s...
<p>Mice were infected with <i>B. burgdorferi</i> for 3 weeks, after which hearts were collected for ...
<div><p>MicroRNA-155 has been shown to play a role in immune activation and inflammation, and is sup...
<p><b>(A)</b> Experimental outline. Two groups of BALB/cByJ mice (n = 4 per group) were vaccinated s...
<p>(A) FACS analysis of cells released from joint tissue of B6 mice uninfected or infected with <i>B...
<p><b>A.)</b> Representative immunoblots with sera of mice infected with <i>B</i>. <i>afzelii</i> st...
<p>BMDM from wild type and TLR2 deficient mice were stimulated with <i>B. burgdorferi</i> (MOI 10) f...
a<p>Mouse infection was determined 3 weeks post inoculation by serological response to <i>B. burgdor...
<p>Cytokines were measured by ELISA in serum collected from B6, Mir155<sup>-/-</sup>, Il10<sup>-/-</...
<p>Bone marrow-derived macrophages (BMDMs) and peritoneal macrophages were isolated from B6, Mir155<...
<p>(A) RNA was isolated from <i>B. burgdorferi</i>-infected rear ankle joints at 2 and 4 weeks post-...
<p>(A) Analysis of cytokine secretion of <i>B. burgdorferi</i>-treated BMDMs. Bone marrow-derived ma...
<p>List of 8 most highly differentially expressed miRNAs in <i>B. burgdorferi</i>-infected joints of...
<p><b>A</b>) BMDM from wild type (B6) and Nod2 deficient mice were stimulated with <i>B. burgdorferi...
<p>(A) Representative flow cytometry analysis of CD11b+ cells released from joint tissue of B6 or B6...
<p>Arthritis severity was determined for <i>B. burgdorferi</i>-infected B6 or B6 miR-146a<sup>−/−</s...
<p>Mice were infected with <i>B. burgdorferi</i> for 3 weeks, after which hearts were collected for ...
<div><p>MicroRNA-155 has been shown to play a role in immune activation and inflammation, and is sup...
<p><b>(A)</b> Experimental outline. Two groups of BALB/cByJ mice (n = 4 per group) were vaccinated s...
<p>(A) FACS analysis of cells released from joint tissue of B6 mice uninfected or infected with <i>B...
<p><b>A.)</b> Representative immunoblots with sera of mice infected with <i>B</i>. <i>afzelii</i> st...
<p>BMDM from wild type and TLR2 deficient mice were stimulated with <i>B. burgdorferi</i> (MOI 10) f...
a<p>Mouse infection was determined 3 weeks post inoculation by serological response to <i>B. burgdor...