Survival rates and mycobacterial burden in the lung and spleen.

<p>Animals were infected with 25 colony-forming units of <i>M</i>.<i>tb</i> Erdman strain. Group coloring in the survival graph is maintained throughout the article for comparability of data. One animal in BCG/Ad(im) group died accidently and is excluded from data analysis (<b>A</b>). Overall log-rank test for trend yielded p = 0.0247, but no statistical differences between groups. Colony-forming units (CFU) of mycobacteria was measured per gram of randomly selected tissue from different lung lobs or spleen at necropsy. CFU per right lung (<b>B</b>), left lung (<b>C</b>) and spleen (<b>D</b>) were presented in logarithmic numbers. P-values above lines indicate comparison between groups. Mann-Whitney rank test is used to compare differences relative to naïve group.