Additional figure 2:

Radiation survival curve of SW1353 cultured in 2D. SW1353 cells were irradiated with the indicated doses of X-rays (low-LET) or 18O ions (high-LET) then plated at low density, as described in methods. The quantification of the number of formed colonies after 11Â days of incubation was used to calculate the surviving fraction relative to the mock-irradiation sample, at each radiation dose. The curve was fitted to the linear quadratic model. Symbols represent the mean of all replicates and error bars represent the SEMs. (JPEG 13Â kb