<p>CD4+ T-lymphocytes (0.5 x 10<sup>6</sup> cells) (triplicates) were exposed to HIV-1 JR-CSF (1 ng of p24) together with DMSO, the HIV-1 protease inhibitor nelfinavir, the HCV NS5A inhibitor daclatasvir and the two CypI ALV and CPI-431-32. Virus and drugs were washed away after 3 h and HIV-1 replication monitored for a period of 2 weeks every 3 days by quantifying amounts of virus in the cell culture supernatant by p24 ELISA (<b>A</b>). Same as A, except Huh7.5.1 hepatoma cells (0.5 x 10<sup>6</sup> cells) (triplicates) were exposed to HCV JFH-1 (1 ng of core) and replication monitored by ELISA for HCV core levels in supernatants (<b>B</b>), by RT-qPCR for HCV RNA levels in supernatants (<b>C</b>) or by colony forming assay for HCV infecti...
In HIV-1/HCV-coinfected patients, chronic HCV infection leads to an increased T-lymphocyte immune ac...
<p>(A) Quantification of HCV-infected target cells (Ti) after co–cultivation with HCV producer cells...
<p>100,000 Huh7.5<sub>JFH1</sub> cells were incubated with infectious HIV<sub>NL4-3</sub> alone, inf...
<p>CD4+ T-lymphocytes (<b>A</b>) and Huh7.5.1 cells (<b>B</b>) (0.5 x 10<sup>6</sup> cells) (triplic...
<p>+/- values represent the standard errors of triplicates. Results are representative of two indepe...
HCV-related liver disease is the main cause of morbidity and mortality of HCV/HIV-1 co-infected pati...
<p>A. <u><i>Mono-infection</i>.</u> Left panel. Activated PBMCs were exposed to HIV-1 JR-CSF (TCID<s...
HCV-related liver disease is the main cause of morbidity and mortality of HCV/HIV-1 co-infected pati...
<p>(A) Huh-7.5.1 cells were treated with various concentrations (0.01 to 50 µM) of PF-429242 for 24 ...
Chronic HCV aff ects millions of people worldwide with major impact on the morbidity and mortality o...
BACKGROUND: Hepatitis C virus (HCV) infection is a major cause of morbidity in HIV infected individu...
BACKGROUND: Hepatitis C virus (HCV) infection is a major cause of morbidity in HIV infected individu...
<p>(A) Cells were infected with HIV (pNL4-3) and incubated with either HCV-positive patient serum (P...
<div><p>(A) The cumulative SI against HCV antigens core, NS3, NS4, and NS5. Four of 60 coinfected pa...
<p>TZM cells were infected with DNase-treated NL4-3 HIV-1 together with DMSO or CPI-431-32 (2 μM). T...
In HIV-1/HCV-coinfected patients, chronic HCV infection leads to an increased T-lymphocyte immune ac...
<p>(A) Quantification of HCV-infected target cells (Ti) after co–cultivation with HCV producer cells...
<p>100,000 Huh7.5<sub>JFH1</sub> cells were incubated with infectious HIV<sub>NL4-3</sub> alone, inf...
<p>CD4+ T-lymphocytes (<b>A</b>) and Huh7.5.1 cells (<b>B</b>) (0.5 x 10<sup>6</sup> cells) (triplic...
<p>+/- values represent the standard errors of triplicates. Results are representative of two indepe...
HCV-related liver disease is the main cause of morbidity and mortality of HCV/HIV-1 co-infected pati...
<p>A. <u><i>Mono-infection</i>.</u> Left panel. Activated PBMCs were exposed to HIV-1 JR-CSF (TCID<s...
HCV-related liver disease is the main cause of morbidity and mortality of HCV/HIV-1 co-infected pati...
<p>(A) Huh-7.5.1 cells were treated with various concentrations (0.01 to 50 µM) of PF-429242 for 24 ...
Chronic HCV aff ects millions of people worldwide with major impact on the morbidity and mortality o...
BACKGROUND: Hepatitis C virus (HCV) infection is a major cause of morbidity in HIV infected individu...
BACKGROUND: Hepatitis C virus (HCV) infection is a major cause of morbidity in HIV infected individu...
<p>(A) Cells were infected with HIV (pNL4-3) and incubated with either HCV-positive patient serum (P...
<div><p>(A) The cumulative SI against HCV antigens core, NS3, NS4, and NS5. Four of 60 coinfected pa...
<p>TZM cells were infected with DNase-treated NL4-3 HIV-1 together with DMSO or CPI-431-32 (2 μM). T...
In HIV-1/HCV-coinfected patients, chronic HCV infection leads to an increased T-lymphocyte immune ac...
<p>(A) Quantification of HCV-infected target cells (Ti) after co–cultivation with HCV producer cells...
<p>100,000 Huh7.5<sub>JFH1</sub> cells were incubated with infectious HIV<sub>NL4-3</sub> alone, inf...