Effect of farnesol on the growth of <i>S</i>. <i>aureus</i> 19552 in mono-microbial biofilms.

<p>(<b>a</b>) Pre-cultered 24h old <i>S</i>. <i>aureus</i> biofilms were supplemented with different concentrations of purified farnesol and the number of cfu`s was determined. <i>S</i>. <i>aureus</i> biofilms incubated in farnesol-free medium were used as control. (<b>b</b>) Growth kinetics of <i>S</i>. <i>aureus</i> in dual biofilms with the farnesol-deficient <i>C</i>. <i>albicans</i> strain ATCC10231 (striped) and the farnesol producer <i>C</i>. <i>albicans</i> SC5314 (open bars). Colony forming units (cfu`s) of <i>S</i>. <i>aureus</i> derived from single species biofilms were function as control (solid bars). Shown are the mean cfu`s and the standard deviations of two representative experiments with three replicates each. Asterisks indicate significant (p<0.05) differences compared to controls.