Parametrization of the model for different species.

<p>Shown in this table are the changes to <i>K</i>_DI, <i>k</i>_M- needed to replicate mouse, rat and human dynamic muscle function. Also shown are metrics of time to peak tension (TPT) and 50%/90%/95% relaxation times (RT₅₀, RT₉₀, RT₉₅) of the dynamic model. Results for force transient are also shown in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1004376#pcbi.1004376.g007" target="_blank">Fig 7</a>. The bottom section shows experimental data ranges used for parametrization of the models. Two sets of results are shown, corresponding to a constant crossbridge unbinding rate (<i>q</i> = 1 in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1004376#pcbi.1004376.e036" target="_blank">Eq 22</a>) and a crossbridge unbinding rate that is variable, modified by the average difference in free energy for the tropomyosin deformation (<i>q</i> = 0.5 in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1004376#pcbi.1004376.e036" target="_blank">Eq 22</a>)</p><p>Parametrization of the model for different species.