<p>Cdh1 is assumed to have 11 phosphorylation levels, as described as Cdh1 (the unphosphorylated form) and Cdh1P through Cdh1P<sub>10</sub>.</p
<div><p>(A) Schematic of independent PSD-localised PP1 enzyme activities for CaMKII and AMPAR. The t...
Mitogen-activated protein kinase (MAPK) cascades can operate as bistable switches residing in either...
<div><p>(A) Phosphorylation of the first subunit is slow at resting Ca<sup>2+</sup> because of the r...
<p>(a) Absolutely bistable models (<i>Bistability</i>>9.5); (b) Bistable models (<i>Bistability</i>>...
<p>Each dashed line indicates the enzyme species on one enzyme-substrate reaction.</p
<p>A schematic of the proposed bistable switch (center panel). The ground state at CpG island chroma...
The abrupt and irreversible transition from interphase to M phase is essential to separate DNA repli...
<p>(A) Self-activating gene with cooperativity. (B) Phosphorylation-dephosphorylation cycle. (C) Sch...
<div><p>CaMKII-thr286* indicates Thr286-phosphorylated CaMKII, and CaMKII-thr286*-thr305* indicates ...
<p>(A) Bifurcation diagram showing the steady state of as a function of . (B) Bistability domain in...
In Fig 7 in the main text we represented the cell cycle as a chain of three bistable switches. Here,...
(A) A schematic of the phosphorylation module. Autophosphorylation and auto-dephosphorylation of the...
Abstract: We analyse a simple kinase model that exhibits bistability when there is no protein turnov...
SummaryPositive feedback loops and double-negative feedback loops can generate bistability, allowing...
We analyse a simple kinase model that exhibits bistability when there is no protein turnover, and sh...
<div><p>(A) Schematic of independent PSD-localised PP1 enzyme activities for CaMKII and AMPAR. The t...
Mitogen-activated protein kinase (MAPK) cascades can operate as bistable switches residing in either...
<div><p>(A) Phosphorylation of the first subunit is slow at resting Ca<sup>2+</sup> because of the r...
<p>(a) Absolutely bistable models (<i>Bistability</i>>9.5); (b) Bistable models (<i>Bistability</i>>...
<p>Each dashed line indicates the enzyme species on one enzyme-substrate reaction.</p
<p>A schematic of the proposed bistable switch (center panel). The ground state at CpG island chroma...
The abrupt and irreversible transition from interphase to M phase is essential to separate DNA repli...
<p>(A) Self-activating gene with cooperativity. (B) Phosphorylation-dephosphorylation cycle. (C) Sch...
<div><p>CaMKII-thr286* indicates Thr286-phosphorylated CaMKII, and CaMKII-thr286*-thr305* indicates ...
<p>(A) Bifurcation diagram showing the steady state of as a function of . (B) Bistability domain in...
In Fig 7 in the main text we represented the cell cycle as a chain of three bistable switches. Here,...
(A) A schematic of the phosphorylation module. Autophosphorylation and auto-dephosphorylation of the...
Abstract: We analyse a simple kinase model that exhibits bistability when there is no protein turnov...
SummaryPositive feedback loops and double-negative feedback loops can generate bistability, allowing...
We analyse a simple kinase model that exhibits bistability when there is no protein turnover, and sh...
<div><p>(A) Schematic of independent PSD-localised PP1 enzyme activities for CaMKII and AMPAR. The t...
Mitogen-activated protein kinase (MAPK) cascades can operate as bistable switches residing in either...
<div><p>(A) Phosphorylation of the first subunit is slow at resting Ca<sup>2+</sup> because of the r...