Table S4. List of proteins involved in important signaling pathways for BCP-ALL. Shown are proteins involved in important signaling pathways for BCP-ALL cell proliferation and survival (e.g. the BCR signaling pathway, the MAPK, PI3 K/Akt/mTOR, JAK/STAT5 signaling pathways), adhesion pathways, and regulators of the cell cycle (including p21Cip1 and p27Kip1). The mean normalized phosphorylation intensities of multiple peptides derived from indicated proteins as well as P-values are shown for IKZF1 deleted (N = 13) and IKZF1 wild type (N = 31) pediatric patients
Table S7. List of Biological processes regulated by CX-4945 incubation. (XLSX 15 kb
Figure S1. CD8+ cells polarized activation in childhood cancer survivors (CCS). Figure S2. Intracell...
Figure S1. Expression of ZFNs proteins in K562 cells. (A) The proteins of K562 cells were collected ...
Table S2. List of 38 differentially phosphorylated peptides. Thirty-eight peptides were differential...
Figure S2. Absolute phosphorylation intensities of 38 differentially phosphorylated peptides. Superv...
Figure S1. Supplementary unsupervised hierarchical clustering. Kinase activity profiles of 45 pediat...
Contains fulltext : 155117.pdf (publisher's version ) (Open Access)BACKGROUND: IKZ...
Table S5. List of genes that were hypomethylated after CX-4945 incubation (FC<0.25) compared to cont...
Table S6. List of genes that were hypomethylated after combined CX-4945 and DEC incubation (FC<0.25)...
Table S3. Complete list of signaling pathways dysregulated in patients who failed to complete remiss...
The expression levels of Sall4 in pediatric ALL clinical specimens. (A) The average expression level...
Treatment resulted in a differential expression of 941 genes ( pâ <â0.05). (PDF 256 kb
Figure S2. KM plots of cytogenetic abnormalities and NER scores. (A) KM plot of cytogenetic abnormal...
Figure S1. The distribution of lncRNAs and PC gene expression and DNA methylation levels across samp...
Table S1. List of the primary antibodies used in this study, and information on working dilutions of...
Table S7. List of Biological processes regulated by CX-4945 incubation. (XLSX 15 kb
Figure S1. CD8+ cells polarized activation in childhood cancer survivors (CCS). Figure S2. Intracell...
Figure S1. Expression of ZFNs proteins in K562 cells. (A) The proteins of K562 cells were collected ...
Table S2. List of 38 differentially phosphorylated peptides. Thirty-eight peptides were differential...
Figure S2. Absolute phosphorylation intensities of 38 differentially phosphorylated peptides. Superv...
Figure S1. Supplementary unsupervised hierarchical clustering. Kinase activity profiles of 45 pediat...
Contains fulltext : 155117.pdf (publisher's version ) (Open Access)BACKGROUND: IKZ...
Table S5. List of genes that were hypomethylated after CX-4945 incubation (FC<0.25) compared to cont...
Table S6. List of genes that were hypomethylated after combined CX-4945 and DEC incubation (FC<0.25)...
Table S3. Complete list of signaling pathways dysregulated in patients who failed to complete remiss...
The expression levels of Sall4 in pediatric ALL clinical specimens. (A) The average expression level...
Treatment resulted in a differential expression of 941 genes ( pâ <â0.05). (PDF 256 kb
Figure S2. KM plots of cytogenetic abnormalities and NER scores. (A) KM plot of cytogenetic abnormal...
Figure S1. The distribution of lncRNAs and PC gene expression and DNA methylation levels across samp...
Table S1. List of the primary antibodies used in this study, and information on working dilutions of...
Table S7. List of Biological processes regulated by CX-4945 incubation. (XLSX 15 kb
Figure S1. CD8+ cells polarized activation in childhood cancer survivors (CCS). Figure S2. Intracell...
Figure S1. Expression of ZFNs proteins in K562 cells. (A) The proteins of K562 cells were collected ...