PKDCC protein family encode for a Serine/threonine/tyrosine protein kinase catalytic domain.

<p>Comparison of the predicted amino acid sequence of mouse (<i>M</i>. <i>musculus</i>) PKDCC with its <i>X</i>. <i>laevis</i> orthologs, Pkdcc1 and Pkdcc2. <i>pkdcc1</i> encodes a 449 a.a. protein with a predicted molecular mass of 51.0 kDa and <i>pkdcc2</i> encodes for a protein with 489 a.a. and 55.9 kDa of predicted molecular mass. Bioinformatic analysis showed that both proteins contain the Serine/Threonine/Tyrosine protein kinase catalytic domain (between a.a. 89 and 336 for Pkdcc1 and between a.a 134 and 381 for Pkdcc2; Grey box, STYKc domain). Identical amino acids among all are shown in red while identical amino acids in only two sequences are shown in blue. The absence of residues at the corresponding region is indicated by dashes.