<p>(A) Confocal images of cochlea hair cells in wild-type mice. LKB1 was expressed from the cuticular plate to the nuclei of hair cells. Left panel: LKB1 expression was detected in the cuticular plate. Right panel: LKB1 expression was detected in the hair cell nuclei. (B) Confocal images of cochlea hair cells in the Atoh1-LKB1<sup>-/-</sup> mice. LKB1 was deleted in the cochlea hair cells of the inner ear. Left panel: LKB1expression was not detected in the cuticular plate. Right panel: LKB1 expression was not detected in the hair cell nuclei. Green, phalloidin, an F-actin specific dye. Red, LKB1. Bule, Dapi. Scale bar: 20 μm.</p
<p><b>Panel A:</b> Cochlea cross-sections immunostained with anti-CDH23 (<b>A–H</b>), anti-PCDH15 (<...
<p>Cochleas were stained with phalloidin, which binds to filamentous actin (red) and anti-prestin an...
<p>Hair cell (HC) loss is irreversible because only very limited HC regeneration has been observed i...
<p>Confocal whole-mount images of cochlea in the control and LKB1 mutant cochlea at P21. Hair cells ...
<p>LKB1 regulates the development and maintenance of hair cell stereociliary bundles in the inner ea...
<p>Brown indicates positive staining. A, B) Expression of Dclk1, showing intense staining in the mar...
<p>(A) There was no significant difference in temporal bones between mutant and wild-type mice at P1...
<p>Upper row, P3; second row P9, and bottom row <i>Lhfpl5</i><sup><i>-/-</i></sup>, P5. Both IHC and...
<p>(A) Upper panel: Western blot analyses demonstrate that S-MLCK (short MLCK) is expressed in mouse...
<p>A–G. Double staining for MYO6 (red: C-ter, A–E and G; N-ter, F) and phalloidin (green) in the coc...
Mechanosensory transduction by vertebrate hair cells depends on a protein complex at the tips of sho...
<p>Brown indicates positive staining. A, B, C, D) Expression of GlyBP showing staining in hair cells...
<p>A: The apical turn in the control group. B: The basal turn in the control group. Three rows of ou...
<p>(A) Immunofluorescence staining of Mst4 was performed using the anti-Mst4 antibody to examine the...
Lipopolysaccharide-responsive beige-like anchor protein (LRBA) belongs to the enigmatic class of BEA...
<p><b>Panel A:</b> Cochlea cross-sections immunostained with anti-CDH23 (<b>A–H</b>), anti-PCDH15 (<...
<p>Cochleas were stained with phalloidin, which binds to filamentous actin (red) and anti-prestin an...
<p>Hair cell (HC) loss is irreversible because only very limited HC regeneration has been observed i...
<p>Confocal whole-mount images of cochlea in the control and LKB1 mutant cochlea at P21. Hair cells ...
<p>LKB1 regulates the development and maintenance of hair cell stereociliary bundles in the inner ea...
<p>Brown indicates positive staining. A, B) Expression of Dclk1, showing intense staining in the mar...
<p>(A) There was no significant difference in temporal bones between mutant and wild-type mice at P1...
<p>Upper row, P3; second row P9, and bottom row <i>Lhfpl5</i><sup><i>-/-</i></sup>, P5. Both IHC and...
<p>(A) Upper panel: Western blot analyses demonstrate that S-MLCK (short MLCK) is expressed in mouse...
<p>A–G. Double staining for MYO6 (red: C-ter, A–E and G; N-ter, F) and phalloidin (green) in the coc...
Mechanosensory transduction by vertebrate hair cells depends on a protein complex at the tips of sho...
<p>Brown indicates positive staining. A, B, C, D) Expression of GlyBP showing staining in hair cells...
<p>A: The apical turn in the control group. B: The basal turn in the control group. Three rows of ou...
<p>(A) Immunofluorescence staining of Mst4 was performed using the anti-Mst4 antibody to examine the...
Lipopolysaccharide-responsive beige-like anchor protein (LRBA) belongs to the enigmatic class of BEA...
<p><b>Panel A:</b> Cochlea cross-sections immunostained with anti-CDH23 (<b>A–H</b>), anti-PCDH15 (<...
<p>Cochleas were stained with phalloidin, which binds to filamentous actin (red) and anti-prestin an...
<p>Hair cell (HC) loss is irreversible because only very limited HC regeneration has been observed i...