<p>During translation (i) ribosomes attach to the first codon with rate <math><mrow><msubsup><mi>k</mi><mn>0</mn><mi>g</mi></msubsup></mrow></math> if the beginning of the mRNA is not occupied by other ribosomes (initiation); (ii) ribosomes move from position <i>i</i> to <i>i</i> + 1 with a site-specific rate <math><mrow><msubsup><mi>k</mi><mi>i</mi><mi>g</mi></msubsup></mrow></math> if not blocked by another ribosome (elongation); and, finally, (iii) after reaching the last codon, they detach with rate <math><mrow><msubsup><mi>k</mi><mi>S</mi><mi>g</mi><mi>g</mi></msubsup></mrow></math> (termination).</p
The translation apparatus has long been viewed as a mere factory until recent findings this last dec...
We investigate the role of degradation of mRNA on protein synthesis using the totally asymmetric sim...
SummaryGene expression can be regulated at the level of initiation of protein biosynthesis via struc...
<p>Particles representing ribosomes move along a unidimensional lattice (the mRNA chain) in which ea...
The translation of messenger RNA transcripts to proteins is commonly modeled as a one-dimensional to...
<p>Ribosomes bind to the first codon of the mRNA with rate <i>α</i> and leave the lattice representi...
<p>The ribosome has three tRNA binding sites, the A, P, and E site. A ribosome that has just arrived...
AbstractWe explore and quantify the physical and biochemical mechanisms that may be relevant in the ...
(A) The transcriptome in the model consists of two types of mRNAs: background mRNAs which are consid...
ABSTRACT We explore and quantify the physical and biochemical mechanisms that may be relevant in the...
Motivation: During translation, ribosomes move linearly along mRNA. In this process, a simultaneous ...
Ribosomes translate messenger RNA (mRNA) into protein in all living cells. The faultless production ...
<p>Ribosomes (shaded in grey), modeled as extended particles that occupy 10 codons (black boxes), jo...
Ribosomes are universally conserved macromolecular machines found within all living cells that catal...
Translational regulation through synonymous codon usage has been recently shown to play an important...
The translation apparatus has long been viewed as a mere factory until recent findings this last dec...
We investigate the role of degradation of mRNA on protein synthesis using the totally asymmetric sim...
SummaryGene expression can be regulated at the level of initiation of protein biosynthesis via struc...
<p>Particles representing ribosomes move along a unidimensional lattice (the mRNA chain) in which ea...
The translation of messenger RNA transcripts to proteins is commonly modeled as a one-dimensional to...
<p>Ribosomes bind to the first codon of the mRNA with rate <i>α</i> and leave the lattice representi...
<p>The ribosome has three tRNA binding sites, the A, P, and E site. A ribosome that has just arrived...
AbstractWe explore and quantify the physical and biochemical mechanisms that may be relevant in the ...
(A) The transcriptome in the model consists of two types of mRNAs: background mRNAs which are consid...
ABSTRACT We explore and quantify the physical and biochemical mechanisms that may be relevant in the...
Motivation: During translation, ribosomes move linearly along mRNA. In this process, a simultaneous ...
Ribosomes translate messenger RNA (mRNA) into protein in all living cells. The faultless production ...
<p>Ribosomes (shaded in grey), modeled as extended particles that occupy 10 codons (black boxes), jo...
Ribosomes are universally conserved macromolecular machines found within all living cells that catal...
Translational regulation through synonymous codon usage has been recently shown to play an important...
The translation apparatus has long been viewed as a mere factory until recent findings this last dec...
We investigate the role of degradation of mRNA on protein synthesis using the totally asymmetric sim...
SummaryGene expression can be regulated at the level of initiation of protein biosynthesis via struc...