Cerebral regions activated by contrasting natural scenes filtered in LSF and HSF to fixation periods, and to each other in young and elderly participants.

<p>A retinotopic organization for spatial frequency processing was observed in young participants: medial activation of the anterior part of the cuneus for LSF (red circles), extending to the retrosplenial cortex (blue circles), and more lateral activation of the posterior part of the cuneus for HFS (green circles). In elderly participants, LSF scene categorization elicited bilateral activation of the retrosplenial (blue circles) cortex, extending to the anterior part of the cuneus (red circles). For illustrative purposes, statistical maps were generated with P < .0001 uncorrected.