PrP-deficiency affects expression of a subset of proteins undergoing pronounced expression levels changes during EMT.

<p>List of proteins exhibiting >20% level differences in comparison of global proteomes of TGFB1-treated stable PrP kd versus wt NMuMG cells (dataset II). Coverage: percentages of primary structure of covered by peptide-to-spectrum matches; # Peptides: number of peptides matched to a given protein entry (note that instances of the same peptide being identified with different modifications counted separately in this tally); Count: number of TMT signature ion distributions, which passed stringent filtering criteria and were used for relative quantitation. Please see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0133741#pone.0133741.s003" target="_blank">S1 Table</a> for complete list of proteins identified, including control samples, confidence scores and statistical measures.