Additional file 9: of Harmful somatic amino acid substitutions affect key pathways in cancers

Contains supplementary Figures S10 to S37. Pathway-based functional interaction network of proteins containing harmful AASs in 28 cancer types. Proteins involved in selected significantly enriched pathways are marked with colored backgrounds. The proteins were clustered into different modules by using ReactomeFI plugin in cytoscape. Figure S10: Acute lymphocytic leukemia (ALL). Figure S11: Acute myeloid leukemia (AML). Figure S12: Bladder cancer. Figure S13: Breast cancer. Figure S14: Cervix cancer. Figure S15: Chronic lymphocytic leukemia (CLL). Figure S16: Colorectum cancer. Figure S17: Esophageal cancer. Figure S18: Glioblastoma. Figure S19: Glioma low grade. Figure S20: Head and neck cancer (HNC). Figure S21: Kidney chromophobe cancer. Figure S22: Kidney clear cell cancer. Figure S23: Kidney papillary cancer. Figure S24: Liver cancer. Figure S25: Lung adeno cancer. Figure S26: Lung small cell cancer. Figure S27: Lung squamous cancer. Figure S28: Lymphoma B-cell. Figure S29: Melanoma cancer. Figure S30: Myeloma cancer. Figure S31: Neuroblastoma. Figure S32: Ovary cancer. Figure S33: Pancreas cancer. Figure S34: Prostate cancer. Figure S35: Stomach cancer. Figure S36: Thyroid cancer. Figure S37: Uterus cancer. (PDF 3125 kb