Additional file 6: of Harmful somatic amino acid substitutions affect key pathways in cancers

This file contains supplementary Figure S7. Distribution of AASs in protein domains. a, Frequency of AASs in protein domains. 20 domains containing the highest frequency of AASs in each cancer are plotted. b, Average frequency of AASs in protein domains in all cancers together. InterPro domains containing at least 2 AASs in at least one of the cancer types are included. (PDF 117 kb