<p><b>A.</b> Compared to normal, CRC showed decreased mRNA expression. <b>B.</b> In HT29 cells, demethylation treatment partly restored mRNA expression. N: normal, CRC: colorectal cancer, AZA: 5-aza-2’-deoxycytidine treatment.</p
In order to study the effect of DNA methylation on gene expression, human cancer cell lines were tre...
<p>Real-time PCR analysis of DYRK2 mRNA expression in sixteen primary colon cancer tissues (T) and a...
Epigenetic regulation of genes involves the coordination of DNA methylation and histone modification...
<p>On the heat map, increased gene expression is represented with red lines, while decreased express...
Background: DNA methylation and histone acetylation are epigenetic modifications that act as regulat...
The identification of genes undergoing genetic or epi-genetic alterations and contributing to the de...
Colorectal Cancer (CRC) is characterized by the accumulation of genetic and epigenetic alterations, ...
SummaryDNA-demethylating agents have shown clinical anti-tumor efficacy via an unknown mechanism of ...
<p>A. Gaedcke's colorectal carcinoma data set: paired normal colon vs paired CRC; B. Skrzypczak's co...
<p>The majority of the genes' expressions, except GSC, TJP1 and MMP3, indicate further malignant dev...
<p><b>A.</b> Changes in the cell cycle distribution of SW48 and HT-29 cells after 72 h of treatment ...
It remains unclear to what extent drugs targeting transcriptional repressor complexes affect global ...
<p>AGS is a GC cell line manifesting hypermethylation of the <i>CLDN11</i> promoter in conjunction w...
<p>(A) The mRNA expression of <i>SRPX2</i> and its homologue <i>SRPX</i> in 15 CRC and paired normal...
SummaryDNA methylation in promoters is well known to silence genes and is the presumed therapeutic t...
In order to study the effect of DNA methylation on gene expression, human cancer cell lines were tre...
<p>Real-time PCR analysis of DYRK2 mRNA expression in sixteen primary colon cancer tissues (T) and a...
Epigenetic regulation of genes involves the coordination of DNA methylation and histone modification...
<p>On the heat map, increased gene expression is represented with red lines, while decreased express...
Background: DNA methylation and histone acetylation are epigenetic modifications that act as regulat...
The identification of genes undergoing genetic or epi-genetic alterations and contributing to the de...
Colorectal Cancer (CRC) is characterized by the accumulation of genetic and epigenetic alterations, ...
SummaryDNA-demethylating agents have shown clinical anti-tumor efficacy via an unknown mechanism of ...
<p>A. Gaedcke's colorectal carcinoma data set: paired normal colon vs paired CRC; B. Skrzypczak's co...
<p>The majority of the genes' expressions, except GSC, TJP1 and MMP3, indicate further malignant dev...
<p><b>A.</b> Changes in the cell cycle distribution of SW48 and HT-29 cells after 72 h of treatment ...
It remains unclear to what extent drugs targeting transcriptional repressor complexes affect global ...
<p>AGS is a GC cell line manifesting hypermethylation of the <i>CLDN11</i> promoter in conjunction w...
<p>(A) The mRNA expression of <i>SRPX2</i> and its homologue <i>SRPX</i> in 15 CRC and paired normal...
SummaryDNA methylation in promoters is well known to silence genes and is the presumed therapeutic t...
In order to study the effect of DNA methylation on gene expression, human cancer cell lines were tre...
<p>Real-time PCR analysis of DYRK2 mRNA expression in sixteen primary colon cancer tissues (T) and a...
Epigenetic regulation of genes involves the coordination of DNA methylation and histone modification...