Expression level of cytokines previously identified as RAO-upregulated.

<p>The graphs represents the expression of <i>IL4R</i>, <i>IL4</i>, and <i>IL10</i> that were identified to have significantly increased expression levels in RAO horses in Family 1 by qRT-PCR [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0136103#pone.0136103.ref018" target="_blank">18</a>]. The x-axes represent the stimulations: no stimulating factor (mock), lipopolysaccharides (LPS), recombinant cyathostomin antigen (RCA), and hay dust extract (HDE). On the logarithmic scaled (log 2) y-axes mean expression values are given in normalized counts per million. Error bars represent 95% confidence intervals. The stars (*) represent significant changes between expression levels of RAO (red dots and lines) and control (green dots and lines) samples at false discovery rate < 0.05.