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IFNα treatment of primary kidney cells derived from wt but not from STAT2 KO hamsters inhibits the replication of adenovirus.

  • Karoly Toth (785339)
  • Sang R. Lee (641951)
  • Baoling Ying (785340)
  • Jacqueline F. Spencer (785341)
  • Ann E. Tollefson (785342)
  • John E. Sagartz (785343)
  • Il-Keun Kong (85884)
  • Zhongde Wang (476556)
  • William S. M. Wold (785344)
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Publication date
August 2015
Icon DOI
10.1371/journal.ppat.1005084.g005

Abstract

<p><b>A.</b> The average of infectious virus yield from two parallel experiments is shown. <b>B.</b> Induction with 250 U of human IFNα results in elevated PKR mRNA levels in wt but not in STAT2 KO primary kidney cells. Individual data from three biological replicates are shown.</p

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