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Overexpression of miR-29a increased histone H3 at lysine 9 (H3K9Ac) and decreased Smad3 expression in HSCs.

  • Ying-Hsien Huang (446595)
  • Mao-Meng Tiao (446593)
  • Li-Tung Huang (280487)
  • Jiin-Haur Chuang (171983)
  • Kuang-Che Kuo (787054)
  • Ya-Ling Yang (664304)
  • Feng-Sheng Wang (787055)
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Publication date
August 2015
Icon DOI
10.1371/journal.pone.0136453.g007

Abstract

<p>A miR-29a mimic and HDAC4 RNAi significantly increased H3K9Ac and decreased both Smad3 and p-Smad3 expression in HSCs of WT mice. Data are expressed as the mean ± SE of four independent experiments. *indicates a p < 0.05 between the groups.</p

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