<p>Direction: RA is risk allele. The odds ratio (OR) is presented for the risk allele, compared with the non-risk allele, for a given model. The FIND ancestry groups are presented in the following order: AA-AI-EA-MA. A “+” or “-”indicates the direction of the effect in individuals of a specific ancestry. A “?” denotes that the indicated SNP did not pass QC in that ancestry and the results were not included in the meta-analysis. *a, additive; r, recessive; d, dominant</p><p>Trans-ethnic meta-analysis GWAS results, across Discovery and Replication samples.</p
<p>Each study is shown by the point estimate of the odds ratio, and a horizontal line denotes the 95...
<p>Rows are as follows: (1) “Totals”: number of samples of a given ancestry in analyzed papers, with...
<p>Eleven independent cross-ethnic T2D risk alleles were combined as an ensemble to calculate the av...
<p><sup>1</sup> P-values shown are additive unless another model is denoted next to the p-value (d =...
Trans-ethnic meta-analysis of genome-wide association studies (GWAS) across diverse populations can ...
The detection of loci contributing effects to complex human traits, and their subsequent fine-mappin...
Trans-ethnic meta-analysis of genome-wide association studies (GWAS) across diverse populations can ...
The detection of loci contributing effects to complex human traits, and their subsequent fine-mappin...
<p>Alleles, MAF, and overall OR are published values. Chr = chromosome. Pos = position in bp. MAF = ...
Summary: Genetic prediction of common complex disease risk is an essential component of precision me...
<p>The genotype is coded for the risk increasing allele, which is the first one mentioned (e.g., T i...
a<p>Model: If the <i>Q-</i>statistic was significant (<i>P</i><0.01), we selected random effects mod...
<p><i>X</i> axis: log(OR) for the replication stage of the discovery European GWAS. <i>Y</i> axis: l...
To further understanding of the genetic basis of type 2 diabetes (T2D) susceptibility, we aggregated...
<p>SNP position were indexed to the forward of NCBI Build 36.3.</p><p>ch: chromosome.</p><p>RA: Risk...
<p>Each study is shown by the point estimate of the odds ratio, and a horizontal line denotes the 95...
<p>Rows are as follows: (1) “Totals”: number of samples of a given ancestry in analyzed papers, with...
<p>Eleven independent cross-ethnic T2D risk alleles were combined as an ensemble to calculate the av...
<p><sup>1</sup> P-values shown are additive unless another model is denoted next to the p-value (d =...
Trans-ethnic meta-analysis of genome-wide association studies (GWAS) across diverse populations can ...
The detection of loci contributing effects to complex human traits, and their subsequent fine-mappin...
Trans-ethnic meta-analysis of genome-wide association studies (GWAS) across diverse populations can ...
The detection of loci contributing effects to complex human traits, and their subsequent fine-mappin...
<p>Alleles, MAF, and overall OR are published values. Chr = chromosome. Pos = position in bp. MAF = ...
Summary: Genetic prediction of common complex disease risk is an essential component of precision me...
<p>The genotype is coded for the risk increasing allele, which is the first one mentioned (e.g., T i...
a<p>Model: If the <i>Q-</i>statistic was significant (<i>P</i><0.01), we selected random effects mod...
<p><i>X</i> axis: log(OR) for the replication stage of the discovery European GWAS. <i>Y</i> axis: l...
To further understanding of the genetic basis of type 2 diabetes (T2D) susceptibility, we aggregated...
<p>SNP position were indexed to the forward of NCBI Build 36.3.</p><p>ch: chromosome.</p><p>RA: Risk...
<p>Each study is shown by the point estimate of the odds ratio, and a horizontal line denotes the 95...
<p>Rows are as follows: (1) “Totals”: number of samples of a given ancestry in analyzed papers, with...
<p>Eleven independent cross-ethnic T2D risk alleles were combined as an ensemble to calculate the av...