Analysis of efficacy outcomes from rating scales and polysomnography.

<p>^aP(Z): The significance of the pooled effect size was determined with Z test.</p><p>^bP(Q): Cochrane’s Q statistic test used to assess the heterogeneity.</p><p>*Number need to treat = 8; 95% CI = 6–13; P(Z)<0.00001; I² = 0; P(Q) = 0.73.</p><p>Abbreviations: 95% CI, 95% confidence interval; CGI-I, Clinical Global Impression-Improvement scale (1–7 scale); CGI-S, Clinical Global Impression-Severity scale (1–7 scale); ISI, Insomnia Severity Index (0–28 scale); LPS, latency to onset of persistent sleep (minutes); PGI-I, Patient Global Impression-Improvement scale (1–7 scale); PGI-S, Patient Global Impression-Severity scale (0–5 scale); N, number of comparisons; n, number of patients; RR, risk ratio; WASO, wakefulness after persistent sleep onset (minutes); WMD, weighted mean difference.</p><p>Analysis of efficacy outcomes from rating scales and polysomnography.