<p>(A) μCT analysis was performed on 12-month-old <i>Osx-Cre</i> (control) and <i>Osx-Cre; Pten</i><sup><i>fl/fl</i></sup> calvaria. (B) Representative coronal calvarial sections from 12-month old mice. Scale bar, 500 μM. (C) Bar graphs showing the calvarial thickness (mean ± SD; n = 6). ***, <i>p</i> < 0.005.</p
To understand the role of tumor suppressor PTEN in cartilage development, we have generated chondroc...
<p>The mRNA levels in the <i>Fam20c</i>-cKO mouse calvaria were expressed as folds of change over th...
<p>(A) TRAP activity staining for osteoclasts (arrows) in decalcified vertebral body sections from 6...
<p>(A) μCT analysis was performed on the distal femur of control, <i>Osx-Cre; Pten</i><sup><i>fl/fl<...
<p>(A) Tibias from 12-month old <i>Osx-Cre</i> (control), <i>Osx-Cre; Pten</i><sup><i>fl/fl</i></sup...
<p>(A) H&E staining of sections from lipoma tumors derived from <i>Osx-Cre; Rb1</i><sup><i>fl/fl</i>...
We used the Cre-loxP system to generate an osteoblast-specific null mutation of Pten in mice [Col1Cr...
In the United States, approximately eight million osseous fractures are reported annually, of which ...
Abstract Background In calvarial mice, mesenchymal stem cells (MSCs) differentiate into osteoprogeni...
<p>(A) PCR analysis of <i>Tsc1</i> allele recombination in tissues from <i>Osx</i>-<i>GFP</i>::<i>Cr...
<p>(A) Graphs show fibroblast-colony forming units (CFU-F) (upper panel) and osteoblast-colony formi...
<p>(A) Primary calvarial osteoblasts were grown to confluence, infected with control or Adeno-Cre, a...
<p><b>A)</b> Illustration of peri- (peri), endo- (endo) and intra- (intra) cranial bone surfaces. <b...
<p>Pregnant C57BL/6 mice were euthanized for examination of fetuses on days 11, 13, 15, 16, 17, and ...
<p>HET and HET-CRE groups were sex- and age matched and at each age and each group had 7 to 11 anima...
To understand the role of tumor suppressor PTEN in cartilage development, we have generated chondroc...
<p>The mRNA levels in the <i>Fam20c</i>-cKO mouse calvaria were expressed as folds of change over th...
<p>(A) TRAP activity staining for osteoclasts (arrows) in decalcified vertebral body sections from 6...
<p>(A) μCT analysis was performed on the distal femur of control, <i>Osx-Cre; Pten</i><sup><i>fl/fl<...
<p>(A) Tibias from 12-month old <i>Osx-Cre</i> (control), <i>Osx-Cre; Pten</i><sup><i>fl/fl</i></sup...
<p>(A) H&E staining of sections from lipoma tumors derived from <i>Osx-Cre; Rb1</i><sup><i>fl/fl</i>...
We used the Cre-loxP system to generate an osteoblast-specific null mutation of Pten in mice [Col1Cr...
In the United States, approximately eight million osseous fractures are reported annually, of which ...
Abstract Background In calvarial mice, mesenchymal stem cells (MSCs) differentiate into osteoprogeni...
<p>(A) PCR analysis of <i>Tsc1</i> allele recombination in tissues from <i>Osx</i>-<i>GFP</i>::<i>Cr...
<p>(A) Graphs show fibroblast-colony forming units (CFU-F) (upper panel) and osteoblast-colony formi...
<p>(A) Primary calvarial osteoblasts were grown to confluence, infected with control or Adeno-Cre, a...
<p><b>A)</b> Illustration of peri- (peri), endo- (endo) and intra- (intra) cranial bone surfaces. <b...
<p>Pregnant C57BL/6 mice were euthanized for examination of fetuses on days 11, 13, 15, 16, 17, and ...
<p>HET and HET-CRE groups were sex- and age matched and at each age and each group had 7 to 11 anima...
To understand the role of tumor suppressor PTEN in cartilage development, we have generated chondroc...
<p>The mRNA levels in the <i>Fam20c</i>-cKO mouse calvaria were expressed as folds of change over th...
<p>(A) TRAP activity staining for osteoclasts (arrows) in decalcified vertebral body sections from 6...