Manhattan Plot of Common Variant Association Analysis with Upper Quartile of PAI-1 distribution.

<p>Only markers on chromosomes 1–22 are presented above; regions from the X chromosome, Y chromosome, pseudo-autosomal region of the X chromosome, and mitochondrial markers have been excluded. Top three significant markers are labeled in bold. Red Line represents FDR significance threshold (2.57 x 10⁻⁶). Loci with more than one significant variant are signified by a box. Noteworthy significant associations are labeled in bold.