<p><b>(A)</b> Steady state distributions of X (total protein) are plotted at <i>J</i><sub><i>0</i></sub> = 3 min<sup>-1</sup> for the QSSA (left panel, mean = 457.2, standard deviation = 42.98, CV = 9.4%) and the mechanistic models (right panel, mean = 462.3, standard deviation = 43.54, CV = 9.42%). <b>(B)</b> Steady state distributions of M<sub>P</sub> (mRNA) are plotted at <i>J</i><sub><i>0</i></sub> = 3 min<sup>-1</sup> for the QSSA (left panel, mean = 185.2, standard deviation = 15.05, CV = 8.13%) and the mechanistic models (right panel, mean = 185.6, standard deviation = 27.26, CV = 14.68%). All the values (except CVs) are in number of molecules.</p
This short note intends to clarify about the applicability of the Stochastic Simulation Algorithm pr...
<p>The plot shows the histogram of the protein abundance (in fractional units) per template. For the...
<p>(A), (B) Power spectra of protein concentrations calculated from 1000 independent Gillespie simul...
Background: In recent years, several stochastic simulation algorithms have been developed to generat...
Abstract: Recent experimental studies elucidating the importance of noise in gene regulation have ig...
<p>Algorithm 1 Gillespie Stochastic Simulation Algorithm <a href="http://www.plosone.org/article/inf...
<p>Upper panel: R protein degradation rate (and other parameters as described in the text) with the...
<p>(A) Gene On/Off states; (B) mRNA numbers; (C) protein numbers. Two simulations when the lengths o...
International audienceStochastic approaches in systems biology are being used increasingly to model ...
<p>Deterministic (A, C) and the corresponding stochastic (B, D) time evolution of RNA, protein and m...
AbstractStochastic approaches in systems biology are being used increasingly to model the heterogene...
<p>(a) Simple three-stage model. Species A, B and C are modeled as coupled linear birth-death proces...
Original paper can be found at: http://www.sciencedirect.com/science/bookseries/00766879 Copyright E...
<p>The histograms (a) and (b) show the simulated results for the steady state protein distributions ...
Recent advances in single-molecule fluorescent imaging have enabled quantitative measurements of tra...
This short note intends to clarify about the applicability of the Stochastic Simulation Algorithm pr...
<p>The plot shows the histogram of the protein abundance (in fractional units) per template. For the...
<p>(A), (B) Power spectra of protein concentrations calculated from 1000 independent Gillespie simul...
Background: In recent years, several stochastic simulation algorithms have been developed to generat...
Abstract: Recent experimental studies elucidating the importance of noise in gene regulation have ig...
<p>Algorithm 1 Gillespie Stochastic Simulation Algorithm <a href="http://www.plosone.org/article/inf...
<p>Upper panel: R protein degradation rate (and other parameters as described in the text) with the...
<p>(A) Gene On/Off states; (B) mRNA numbers; (C) protein numbers. Two simulations when the lengths o...
International audienceStochastic approaches in systems biology are being used increasingly to model ...
<p>Deterministic (A, C) and the corresponding stochastic (B, D) time evolution of RNA, protein and m...
AbstractStochastic approaches in systems biology are being used increasingly to model the heterogene...
<p>(a) Simple three-stage model. Species A, B and C are modeled as coupled linear birth-death proces...
Original paper can be found at: http://www.sciencedirect.com/science/bookseries/00766879 Copyright E...
<p>The histograms (a) and (b) show the simulated results for the steady state protein distributions ...
Recent advances in single-molecule fluorescent imaging have enabled quantitative measurements of tra...
This short note intends to clarify about the applicability of the Stochastic Simulation Algorithm pr...
<p>The plot shows the histogram of the protein abundance (in fractional units) per template. For the...
<p>(A), (B) Power spectra of protein concentrations calculated from 1000 independent Gillespie simul...