Ischemic lesions of striatum elicit secondary changes in ipsilateral substantia nigra.

<p>(A) Color coding of the relative frequency of “ischemic” voxels in the primary ischemic lesion of striatal stroke patients (n = 12) who subsequently developed secondary midbrain changes. Cd: Caudate nucleus (n_max = 11); Pu: putamen (n_max = 10). (B) Color coding of the relative frequency of voxels showing secondary changes in midbrain in these patients. SNC: substantia nigra, pars compacta (n_max = 9). SNR: substantia nigra, pars reticulata. Numbers ranging from -12.5 to +21.2 denote Talairach y-coordinates.