(CSV 7Â kb)Intracellular metabolite concentrations in the parent and tolerant strains
Additional file 1: Fig. S1. The growth rate of KM and KM-100d at different ethanol concentrations. F...
Relative abundance of microbial species in the metagenomes (the percentage of overall microbial abun...
Additional phenotypic information. Concentrations of determined secondary metabolites produced by th...
(CSV 3Â kb)Â Point mutations and indels found in the parent strains in comparison with W3110 referen...
(CSV 876Â kb)Time series expression analysis. The expression levels of 6 independent culture series ...
Reproducibility of (a) transcriptome analysis, (b) metabolome analysis. Horizontal and vertical axis...
Correlations between gene expression changes for all possible pairs of tolerant strains. Each axis r...
Expression changes of genes related to (a) arginine, (b) methionine, and (c) histidine biosynthesis ...
Metabolite concentrations in de novo and salvage purine biosynthesis. In each inset, the vertical ax...
Growth rates of isolated clones from the end-point populations of (a) strain E and (b) strain F. Gro...
Expression changes of genes related to the biosynthesis of phosphoribosyl pyrophosphate (PRPP) in to...
Sequence coverage of strain C. The number of mapped sequencing reads of Illumina analysis is plotted...
Additional file 4. Genes involved in pathways closely related to ethanol tolerance. A file containin...
Table S1. List of observed nucleotide changes in FBR5 and the twenty mutant strains derived from FBR...
Hybrid growth did not slow-down during ethanol stress. (A) For the S. cerevisiae pool, long-term sur...
Additional file 1: Fig. S1. The growth rate of KM and KM-100d at different ethanol concentrations. F...
Relative abundance of microbial species in the metagenomes (the percentage of overall microbial abun...
Additional phenotypic information. Concentrations of determined secondary metabolites produced by th...
(CSV 3Â kb)Â Point mutations and indels found in the parent strains in comparison with W3110 referen...
(CSV 876Â kb)Time series expression analysis. The expression levels of 6 independent culture series ...
Reproducibility of (a) transcriptome analysis, (b) metabolome analysis. Horizontal and vertical axis...
Correlations between gene expression changes for all possible pairs of tolerant strains. Each axis r...
Expression changes of genes related to (a) arginine, (b) methionine, and (c) histidine biosynthesis ...
Metabolite concentrations in de novo and salvage purine biosynthesis. In each inset, the vertical ax...
Growth rates of isolated clones from the end-point populations of (a) strain E and (b) strain F. Gro...
Expression changes of genes related to the biosynthesis of phosphoribosyl pyrophosphate (PRPP) in to...
Sequence coverage of strain C. The number of mapped sequencing reads of Illumina analysis is plotted...
Additional file 4. Genes involved in pathways closely related to ethanol tolerance. A file containin...
Table S1. List of observed nucleotide changes in FBR5 and the twenty mutant strains derived from FBR...
Hybrid growth did not slow-down during ethanol stress. (A) For the S. cerevisiae pool, long-term sur...
Additional file 1: Fig. S1. The growth rate of KM and KM-100d at different ethanol concentrations. F...
Relative abundance of microbial species in the metagenomes (the percentage of overall microbial abun...
Additional phenotypic information. Concentrations of determined secondary metabolites produced by th...