(CSV 3Â kb)Â Point mutations and indels found in the parent strains in comparison with W3110 reference genome
The list of coding mutations acquired by the strain lineage of P. chrysogenum. (XLSX 52 kb
The number of directional comparisons in each principal component, along with the percent variation ...
Additional file 2. DNA mutations in KM-100d compared to KM. A file containing SNP mutation sites and...
(CSV 7Â kb)Intracellular metabolite concentrations in the parent and tolerant strains
Correlations between gene expression changes for all possible pairs of tolerant strains. Each axis r...
(CSV 876Â kb)Time series expression analysis. The expression levels of 6 independent culture series ...
Sequence coverage of strain C. The number of mapped sequencing reads of Illumina analysis is plotted...
Reproducibility of (a) transcriptome analysis, (b) metabolome analysis. Horizontal and vertical axis...
Growth rates of isolated clones from the end-point populations of (a) strain E and (b) strain F. Gro...
Expression changes of genes related to (a) arginine, (b) methionine, and (c) histidine biosynthesis ...
Table S1. List of observed nucleotide changes in FBR5 and the twenty mutant strains derived from FBR...
Metabolite concentrations in de novo and salvage purine biosynthesis. In each inset, the vertical ax...
Expression changes of genes related to the biosynthesis of phosphoribosyl pyrophosphate (PRPP) in to...
Hybrid growth did not slow-down during ethanol stress. (A) For the S. cerevisiae pool, long-term sur...
Efficient production of ethanol for use as a renewable fuel requires organisms with a high level of ...
The list of coding mutations acquired by the strain lineage of P. chrysogenum. (XLSX 52 kb
The number of directional comparisons in each principal component, along with the percent variation ...
Additional file 2. DNA mutations in KM-100d compared to KM. A file containing SNP mutation sites and...
(CSV 7Â kb)Intracellular metabolite concentrations in the parent and tolerant strains
Correlations between gene expression changes for all possible pairs of tolerant strains. Each axis r...
(CSV 876Â kb)Time series expression analysis. The expression levels of 6 independent culture series ...
Sequence coverage of strain C. The number of mapped sequencing reads of Illumina analysis is plotted...
Reproducibility of (a) transcriptome analysis, (b) metabolome analysis. Horizontal and vertical axis...
Growth rates of isolated clones from the end-point populations of (a) strain E and (b) strain F. Gro...
Expression changes of genes related to (a) arginine, (b) methionine, and (c) histidine biosynthesis ...
Table S1. List of observed nucleotide changes in FBR5 and the twenty mutant strains derived from FBR...
Metabolite concentrations in de novo and salvage purine biosynthesis. In each inset, the vertical ax...
Expression changes of genes related to the biosynthesis of phosphoribosyl pyrophosphate (PRPP) in to...
Hybrid growth did not slow-down during ethanol stress. (A) For the S. cerevisiae pool, long-term sur...
Efficient production of ethanol for use as a renewable fuel requires organisms with a high level of ...
The list of coding mutations acquired by the strain lineage of P. chrysogenum. (XLSX 52 kb
The number of directional comparisons in each principal component, along with the percent variation ...
Additional file 2. DNA mutations in KM-100d compared to KM. A file containing SNP mutation sites and...
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