<p>J774 macrophages were incubated with cAMP to increase the ABCA1 expression and then CER-001 and HDL3 at 25 μg/ml were added in the cell culture medium and the specific cAMP cholesterol efflux was determined. apoA-I (25 μg/ml) was used as reference for specific ABCA1-cholesterol efflux in the experiment. ** p<0.01, ***p<0.001.</p
International audienceRationale: High-density lipoprotein (HDL) is a heterogeneous population of par...
OBJECTIVE: To investigate whether the morphological and functional changes typical of cell immobiliz...
Most types of cells in the body have no or very limited capacity of catabolizing cholesterol, so cho...
<p>J774 macrophages enriched with <sup>3</sup>H-cholesterol were incubated with apoA-I WT or A164S a...
<p>Panel A; ABCA1 mRNA level in J774 macrophages was determined in presence of different concentrati...
<p>(<b>A</b>) J774 cells were incubated 24 hrs with 25 µg/ml Acetylated LDL+2 µg/ml Sandoz ACAT inhi...
Objectives: ATP-binding cassette transporter A1 (ABCA1) is a key player in the reverse cholesterol t...
<p>PBMCs were isolated from subjects and differentiated into macrophages using 20/mL M-CSF for 7 day...
<p>Cells were incubated with 100 µg/ml AcLDL for 6 h and treated with 3 µg/ml U18666A or without (co...
International audienceObjective— Maintenance of cholesterol homeostasis in human macrophages is esse...
<p>J774 mouse macrophages were labeled with [<sup>14</sup>C]cholesterol (A) or [<sup>14</sup>C]chole...
ABCA1, a member of the ATP-binding cassette family, mediates the efflux of cellular lipids to free a...
We investigated the interaction of oxidized low density lipoprotein (OxLDL) with the ATP-binding cas...
Objective—Maintenance of cholesterol homeostasis in human macrophages is essential to prevent foam c...
<p>(A) Cell toxicity of GW3965. Huh7.5 cells were cultured in the presence of indicated concentratio...
International audienceRationale: High-density lipoprotein (HDL) is a heterogeneous population of par...
OBJECTIVE: To investigate whether the morphological and functional changes typical of cell immobiliz...
Most types of cells in the body have no or very limited capacity of catabolizing cholesterol, so cho...
<p>J774 macrophages enriched with <sup>3</sup>H-cholesterol were incubated with apoA-I WT or A164S a...
<p>Panel A; ABCA1 mRNA level in J774 macrophages was determined in presence of different concentrati...
<p>(<b>A</b>) J774 cells were incubated 24 hrs with 25 µg/ml Acetylated LDL+2 µg/ml Sandoz ACAT inhi...
Objectives: ATP-binding cassette transporter A1 (ABCA1) is a key player in the reverse cholesterol t...
<p>PBMCs were isolated from subjects and differentiated into macrophages using 20/mL M-CSF for 7 day...
<p>Cells were incubated with 100 µg/ml AcLDL for 6 h and treated with 3 µg/ml U18666A or without (co...
International audienceObjective— Maintenance of cholesterol homeostasis in human macrophages is esse...
<p>J774 mouse macrophages were labeled with [<sup>14</sup>C]cholesterol (A) or [<sup>14</sup>C]chole...
ABCA1, a member of the ATP-binding cassette family, mediates the efflux of cellular lipids to free a...
We investigated the interaction of oxidized low density lipoprotein (OxLDL) with the ATP-binding cas...
Objective—Maintenance of cholesterol homeostasis in human macrophages is essential to prevent foam c...
<p>(A) Cell toxicity of GW3965. Huh7.5 cells were cultured in the presence of indicated concentratio...
International audienceRationale: High-density lipoprotein (HDL) is a heterogeneous population of par...
OBJECTIVE: To investigate whether the morphological and functional changes typical of cell immobiliz...
Most types of cells in the body have no or very limited capacity of catabolizing cholesterol, so cho...