Location of 14 mutations in the α7 nAChR receptor.
- Qinhui Zhang (763125)
- Yingjie Du (792143)
- Jianliang Zhang (448868)
- Xiaojun Xu (153741)
- Fenqin Xue (792144)
- Cong Guo (412764)
- Yao Huang (216100)
- Ronald J. Lukas (781724)
- Yongchang Chang (216099)
Publication date
September 2015
DOIAbstract
<p>A: The residues with the mutations in the binding region (loops A (TYR93), and C (CYS191, LYS192, ASP197) of the principal side of a binding pocket, and D (TRP55) of the complementary side of the neighboring binding pocket); B, The residues with the mutations in the coupling region (loop 2 (ASN47), loop 9 (ASN171 and GLU173), pre-M1 (ARG205 and ARG206) and M1 (TYR211 and GLY212).</p
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