A: Fluorescent microscopy images of MiaPaCa-2 cells treated with Rhodamin-labeled liposomes for 4 hours. Green fluorescence shows lysosomes, stained with LysoTracker (Life Technologies). Red fluorescence shows Rhodamin-labeled liposomes. B: Dynamic light scattering of GGTI-loaded liposome is shown. GGTI-loaded liposomes were prepared as described in Materials and Methods. C: Low pH release of GGTI from GGTI-loaded liposomes.

<p>GGTI-loaded liposomes were prepared and then exposed to solution adjusted to different pH values for 15 min and the release of GGTI was examined by HPLC. TritonX-100 was used as a full release control. The symbol * indicates statistically significant difference at P value < 0.05.