Effect of constant and acute light during the scotophase on GEFS+ and control sleep.

<p><b>(A)</b> Sleep profiles of control (<i>n</i> = 83) and GEFS+ (<i>n</i> = 95) flies under constant light/light (LL) exposure. <b>(B)</b> Total sleep and <b>(C)</b> sleep latency during subjective night under LD and LL conditions; Rank Sum Tests. <b>(D)</b> Sleep and <b>(E)</b> activity profiles of control (<i>n</i> = 52) and GEFS+ (<i>n</i> = 59) flies subjected to a 1 hr scotophase light pulse; repeated measures ANOVA on Ranks. <b>(F)</b> Sleep latencies of control and GEFS+ flies after normal lights off (12 hr and 36 hr) and the scotophase pulse (42 hr); ANOVA on Ranks, Dunn’s vs 12 hr control. Data presented as averages with SEM (<b>A</b>, <b>D</b> and <b>E</b>) or boxplots with means (“X”) (<b>B</b>, <b>C</b> and <b>F</b>); ***p < 0.001.