Mortality prediction based on the plasma levels of the biomarkers and on the severity scores according to ROC curve analysis.

<p>The optimal cutoff values for each plasma biomarker level and the severity scores are presented. A <i>p</i>-value < 0.05 was considered to be statistically significant.</p><p>CIRP = cold-inducible RNA-binding protein, APACHE II = Acute Physiology and Chronic Health Evaluation II, SOFA = Sequential Organ Failure Assessment score, PCT = procalcitonin, WBC = white blood cell, N% = neutrophil ratio.</p><p>ROC = receiver operating characteristic, AUC = area under the ROC curve, CI = confidence interval.</p><p>^b<i>p</i> = 0.000437.</p><p>Mortality prediction based on the plasma levels of the biomarkers and on the severity scores according to ROC curve analysis.