Change in CTC dynamics after surgery.

<p>(A) Profile plot of CTC detection rates (in CTCs/minute) measured weekly from six mice inoculated with breast cancer cells (MDA-MB-LUC2-GFP). Surgery was conducted at Week 2 after tumor inoculation. (B) Profile plot of the average number of CTC signals per minute and average tumor volume during eight weeks from n = 5 mice after excluding the mouse which received partial tumor resection. Values and error bars represent the averages and SDs of CTC counts from n = 5 mice. (C) Individual tumor volumes from six mice. Surgery was performed at week 2 after tumor inoculation. (D) Profile plot of the average number of CTC signals per minute from 60 min before and 120 min after the surgery.