Ferric-reducing antioxidant power (FRAP; upper panel) and Superoxide dismutase (SOD; lower panel) plasma values (mean ± SD) before (Pre) and immediately following (Post) the normobaric (NH) and hypobaric (HH) LHTL protocol.

Hct and platelet count at T0, T30,T60, and T90.

Yu-ming Zhang (424846)
Bo Gao (106513)
Juan-juan Wang (424847)
Xu-de Sun (5655373)
Xi-wen Liu (424848)

June 2013

*P<0.001: group HS-HR vs. group HS-NR. #P<0.001: group HS-HR vs. group HS-NR. Group Sham: sham op...

Comparison of Hematologic and Organ Function Parameters at Enrollment and Last visits in Patients with HbSS Based on Hydroxyurea Status and Fetal Hemoglobin Quartile.

Courtney D. Fitzhugh (827823)
Matthew M. Hsieh (267806)
Darlene Allen (479951)
Wynona A. Coles (827824)
Cassie Seamon (827825)
Michael Ring (827826)
Xiongce Zhao (385969)
Caterina P. Minniti (369129)
Griffin P. Rodgers (827827)
Alan N. Schechter (99551)
John F. Tisdale (267811)
James G. Taylor VI (271944)

November 2015

Abbreviations: HU, hydroxyurea; Low HbF, maximum fetal hemoglobin within the lowest quartile; Hig...

Pre- and postdialytic blood pressures.

Christian Daugaard Peters (748219)
Krista Dybtved Kjaergaard (748220)
Jens Dam Jensen (748221)
Kent Lodberg Christensen (748222)
Charlotte Strandhave (748223)
Ida Noerager Tietze (748224)
Marija Kristina Novosel (748225)
Bo Martin Bibby (346318)
Bente Jespersen (550700)

June 2015

Fig 2A-B is reused from our previous publication but is slightly modified compared to the origina...

Advanced oxidation protein products (AOPP; upper panel) and nitrotyrosine (lower panel) plasma values (mean ± SD) before (Pre) and immediately following (Post) the normobaric (NH) and hypobaric (HH) LHTL protocol.

Tadej Debevec (571217)
Vincent Pialoux (713546)
Jonas Saugy (427333)
Laurent Schmitt (444157)
Roberto Cejuela (675951)
Pauline Mury (795199)
Sabine Ehrström (795200)
Raphael Faiss (379985)
Grégoire P. Millet (379991)

September 2015

Significant post hoc differences: ** P < 0.01 vs. Pre value; # P < 0.05 vs. corresp...

NO metabolism end-products (NOx: upper panel) and plasma uric acid (UA) values (mean ± SD) before (Pre) and immediately following (Post) the normobaric (NH) and hypobaric (HH) LHTL protocol.

Tadej Debevec (571217)
Vincent Pialoux (713546)
Jonas Saugy (427333)
Laurent Schmitt (444157)
Roberto Cejuela (675951)
Pauline Mury (795199)
Sabine Ehrström (795200)
Raphael Faiss (379985)
Grégoire P. Millet (379991)

September 2015

Significant post hoc differences: ** P < 0.01 vs. Pre value; # P < 0.05 vs. corresp...

Plasma values of select oxidative stress and antioxidant markers obtained before (Pre) and immediately following (Post) the live-high train-low (LHTL) protocol in NH and HH.

Tadej Debevec (571217)
Vincent Pialoux (713546)
Jonas Saugy (427333)
Laurent Schmitt (444157)
Roberto Cejuela (675951)
Pauline Mury (795199)
Sabine Ehrström (795200)
Raphael Faiss (379985)
Grégoire P. Millet (379991)

September 2015

Values are presented as mean ± SD. NH, normobaric live-high train-low protocol (N = 24); H...

Comparisons of biochemical parameters before and after HVHF.

Xiaoyun Si (775186)
Jingjing Li (7654)
Xiaohong Bi (775187)
Lan Wu (326399)
Xiaoyan Wu (235931)

July 2015

Note: Data are shown as the mean ± standard deviation.* P < 0.05 vs. ...

Plasma lactate at T0, T30, T60, and T90.

Yu-ming Zhang (424846)
Bo Gao (106513)
Juan-juan Wang (424847)
Xu-de Sun (5655373)
Xi-wen Liu (424848)

June 2013

*P<0.001: group HS-HR vs. group HS-NR. #P<0.001: group HS-HR vs. group HS-NR. Group Sham: sham op...

Plasma glutathione and MDA levels, and total urinary excretion of hydrogen peroxide and of isoprostanes.

Carla Ferreyra (463393)
Félix Vargas (316958)
Isabel Rodríguez-Gómez (5656501)
Rocío Pérez-Abud (463394)
Francisco O'Valle (35543)
Antonio Osuna (316961)

September 2013

(Upper panels) Plasma glutathione and MDA levels, and (lower panels) total urinary excretion of h...

DPPH radical scavenging, HRS, RP, and ILAP values vs. CAA indexes for the different CFSs and MRS broth.

Jiali Xing (706160)
Gang Wang (36685)
Qiuxiang Zhang (216630)
Xiaoming Liu (47653)
Zhennan Gu (193159)
Hao Zhang (15339)
Yong Q. Chen (193277)
Wei Chen (23863)

March 2015

(A) CAA values vs DPPH radical scavenging and ILAP indexes for CFSs and MRS broth. (B) CAA values...

Relative mean power output during time-trial.

Eric A. Carter (468861)
A. William Sheel (6239666)
William K. Milsom (548289)
Michael S. Koehle (468869)

January 2019

PN, placebo in normoxia; PH, placebo in hypoxia; SH, sildenafil in hypoxia; *Indicates normoxic valu...

HT decreases the oxidative stress level only in hypoxic conditions.

Jesús Calahorra (5774630)
Esther Martínez-Lara (5774633)
Cristina De Dios (5774636)
Eva Siles (5774639)

September 2018

Oxidative stress level measured by DCF fluorescence in (A) normoxic cells and (B) hypoxic cells. Val...

Fig 4 -

Eleanor Brindle (677213)
Lorraine Lillis (636096)
Rebecca Barney (436440)
Pooja Bansil (2585788)
Francisco Arredondo (11648405)
Neal E. Craft (11648408)
Eileen Murphy (2347456)
David S. Boyle (9212627)

November 2022

A. Bland Altman plots of the difference in results derived from wet plasma versus DBS types measured...

TLQP-21 treatment (72 h) protects the HUVECs from oxidative stress by intercellularly rebalancing the redox state.

Wei Zhang (405)
Chao Ni (402065)
Jie Sheng (299401)
Yanyin Hua (286561)
Jiangbo Ma (488346)
Lijun Wang (176511)
Yu Zhao (104852)
Yubo Xing (424909)

November 2013

(A) GSH level of HUVECs with different treatments. (B) SOD activity of HUVECs with different trea...

Secondary endpoints – Hematologic parameters (% [n] or mean [SD]) (ITT).

Bernard Favrat (105884)
Katharina Balck (582781)
Christian Breymann (582782)
Michael Hedenus (582783)
Thomas Keller (67075)
Anna Mezzacasa (582784)
Christoph Gasche (117548)

April 2014

‡A positive value of the difference FCM–placebo is in favor of FCM;§Mean Hb levels at Day ...

Hct and platelet count at T0, T30,T60, and T90.

Yu-ming Zhang (424846)
Bo Gao (106513)
Juan-juan Wang (424847)
Xu-de Sun (5655373)
Xi-wen Liu (424848)

June 2013

*P<0.001: group HS-HR vs. group HS-NR. #P<0.001: group HS-HR vs. group HS-NR. Group Sham: sham op...

Comparison of Hematologic and Organ Function Parameters at Enrollment and Last visits in Patients with HbSS Based on Hydroxyurea Status and Fetal Hemoglobin Quartile.

Courtney D. Fitzhugh (827823)
Matthew M. Hsieh (267806)
Darlene Allen (479951)
Wynona A. Coles (827824)
Cassie Seamon (827825)
Michael Ring (827826)
Xiongce Zhao (385969)
Caterina P. Minniti (369129)
Griffin P. Rodgers (827827)
Alan N. Schechter (99551)
John F. Tisdale (267811)
James G. Taylor VI (271944)

November 2015

Abbreviations: HU, hydroxyurea; Low HbF, maximum fetal hemoglobin within the lowest quartile; Hig...

Pre- and postdialytic blood pressures.

Christian Daugaard Peters (748219)
Krista Dybtved Kjaergaard (748220)
Jens Dam Jensen (748221)
Kent Lodberg Christensen (748222)
Charlotte Strandhave (748223)
Ida Noerager Tietze (748224)
Marija Kristina Novosel (748225)
Bo Martin Bibby (346318)
Bente Jespersen (550700)

June 2015

Fig 2A-B is reused from our previous publication but is slightly modified compared to the origina...

Advanced oxidation protein products (AOPP; upper panel) and nitrotyrosine (lower panel) plasma values (mean ± SD) before (Pre) and immediately following (Post) the normobaric (NH) and hypobaric (HH) LHTL protocol.

Tadej Debevec (571217)
Vincent Pialoux (713546)
Jonas Saugy (427333)
Laurent Schmitt (444157)
Roberto Cejuela (675951)
Pauline Mury (795199)
Sabine Ehrström (795200)
Raphael Faiss (379985)
Grégoire P. Millet (379991)

September 2015

Significant post hoc differences: ** P < 0.01 vs. Pre value; # P < 0.05 vs. corresp...

NO metabolism end-products (NOx: upper panel) and plasma uric acid (UA) values (mean ± SD) before (Pre) and immediately following (Post) the normobaric (NH) and hypobaric (HH) LHTL protocol.

Tadej Debevec (571217)
Vincent Pialoux (713546)
Jonas Saugy (427333)
Laurent Schmitt (444157)
Roberto Cejuela (675951)
Pauline Mury (795199)
Sabine Ehrström (795200)
Raphael Faiss (379985)
Grégoire P. Millet (379991)

September 2015

Significant post hoc differences: ** P < 0.01 vs. Pre value; # P < 0.05 vs. corresp...

Plasma values of select oxidative stress and antioxidant markers obtained before (Pre) and immediately following (Post) the live-high train-low (LHTL) protocol in NH and HH.

Tadej Debevec (571217)
Vincent Pialoux (713546)
Jonas Saugy (427333)
Laurent Schmitt (444157)
Roberto Cejuela (675951)
Pauline Mury (795199)
Sabine Ehrström (795200)
Raphael Faiss (379985)
Grégoire P. Millet (379991)

September 2015

Values are presented as mean ± SD. NH, normobaric live-high train-low protocol (N = 24); H...

Comparisons of biochemical parameters before and after HVHF.

Xiaoyun Si (775186)
Jingjing Li (7654)
Xiaohong Bi (775187)
Lan Wu (326399)
Xiaoyan Wu (235931)

July 2015

Note: Data are shown as the mean ± standard deviation.* P < 0.05 vs. ...

Plasma lactate at T0, T30, T60, and T90.

Yu-ming Zhang (424846)
Bo Gao (106513)
Juan-juan Wang (424847)
Xu-de Sun (5655373)
Xi-wen Liu (424848)

June 2013

*P<0.001: group HS-HR vs. group HS-NR. #P<0.001: group HS-HR vs. group HS-NR. Group Sham: sham op...

Plasma glutathione and MDA levels, and total urinary excretion of hydrogen peroxide and of isoprostanes.

Carla Ferreyra (463393)
Félix Vargas (316958)
Isabel Rodríguez-Gómez (5656501)
Rocío Pérez-Abud (463394)
Francisco O'Valle (35543)
Antonio Osuna (316961)

September 2013

(Upper panels) Plasma glutathione and MDA levels, and (lower panels) total urinary excretion of h...

DPPH radical scavenging, HRS, RP, and ILAP values vs. CAA indexes for the different CFSs and MRS broth.

Jiali Xing (706160)
Gang Wang (36685)
Qiuxiang Zhang (216630)
Xiaoming Liu (47653)
Zhennan Gu (193159)
Hao Zhang (15339)
Yong Q. Chen (193277)
Wei Chen (23863)

March 2015

(A) CAA values vs DPPH radical scavenging and ILAP indexes for CFSs and MRS broth. (B) CAA values...

Relative mean power output during time-trial.

Eric A. Carter (468861)
A. William Sheel (6239666)
William K. Milsom (548289)
Michael S. Koehle (468869)

January 2019

PN, placebo in normoxia; PH, placebo in hypoxia; SH, sildenafil in hypoxia; *Indicates normoxic valu...

HT decreases the oxidative stress level only in hypoxic conditions.

Jesús Calahorra (5774630)
Esther Martínez-Lara (5774633)
Cristina De Dios (5774636)
Eva Siles (5774639)

September 2018

Oxidative stress level measured by DCF fluorescence in (A) normoxic cells and (B) hypoxic cells. Val...

Fig 4 -

Eleanor Brindle (677213)
Lorraine Lillis (636096)
Rebecca Barney (436440)
Pooja Bansil (2585788)
Francisco Arredondo (11648405)
Neal E. Craft (11648408)
Eileen Murphy (2347456)
David S. Boyle (9212627)

November 2022

A. Bland Altman plots of the difference in results derived from wet plasma versus DBS types measured...

TLQP-21 treatment (72 h) protects the HUVECs from oxidative stress by intercellularly rebalancing the redox state.

Wei Zhang (405)
Chao Ni (402065)
Jie Sheng (299401)
Yanyin Hua (286561)
Jiangbo Ma (488346)
Lijun Wang (176511)
Yu Zhao (104852)
Yubo Xing (424909)

November 2013

(A) GSH level of HUVECs with different treatments. (B) SOD activity of HUVECs with different trea...

Secondary endpoints – Hematologic parameters (% [n] or mean [SD]) (ITT).

Bernard Favrat (105884)
Katharina Balck (582781)
Christian Breymann (582782)
Michael Hedenus (582783)
Thomas Keller (67075)
Anna Mezzacasa (582784)
Christoph Gasche (117548)

April 2014

‡A positive value of the difference FCM–placebo is in favor of FCM;§Mean Hb levels at Day ...

Hct and platelet count at T0, T30,T60, and T90.

Yu-ming Zhang (424846)
Bo Gao (106513)
Juan-juan Wang (424847)
Xu-de Sun (5655373)
Xi-wen Liu (424848)

June 2013

*P<0.001: group HS-HR vs. group HS-NR. #P<0.001: group HS-HR vs. group HS-NR. Group Sham: sham op...

Comparison of Hematologic and Organ Function Parameters at Enrollment and Last visits in Patients with HbSS Based on Hydroxyurea Status and Fetal Hemoglobin Quartile.

Courtney D. Fitzhugh (827823)
Matthew M. Hsieh (267806)
Darlene Allen (479951)
Wynona A. Coles (827824)
Cassie Seamon (827825)
Michael Ring (827826)
Xiongce Zhao (385969)
Caterina P. Minniti (369129)
Griffin P. Rodgers (827827)
Alan N. Schechter (99551)
John F. Tisdale (267811)
James G. Taylor VI (271944)

November 2015

Abbreviations: HU, hydroxyurea; Low HbF, maximum fetal hemoglobin within the lowest quartile; Hig...

Pre- and postdialytic blood pressures.

Christian Daugaard Peters (748219)
Krista Dybtved Kjaergaard (748220)
Jens Dam Jensen (748221)
Kent Lodberg Christensen (748222)
Charlotte Strandhave (748223)
Ida Noerager Tietze (748224)
Marija Kristina Novosel (748225)
Bo Martin Bibby (346318)
Bente Jespersen (550700)

June 2015

Fig 2A-B is reused from our previous publication but is slightly modified compared to the origina...

Ferric-reducing antioxidant power (FRAP; upper panel) and Superoxide dismutase (SOD; lower panel) plasma values (mean ± SD) before (Pre) and immediately following (Post) the normobaric (NH) and hypobaric (HH) LHTL protocol.

Abstract

Extracted data

Ferric-reducing antioxidant power (FRAP; upper panel) and Superoxide dismutase (SOD; lower panel) plasma values (mean ± SD) before (Pre) and immediately following (Post) the normobaric (NH) and hypobaric (HH) LHTL protocol.

Abstract

Extracted data

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