Histological analysis of CDKN3 protein expression.

<p>CDKN3 protein expression was determined by immunohistochemistry using formalin-fixed paraffin-embedded tissue sections. Representative experiments in HPV16-positive squamous cell carcinomas (A–D) and adenocarcinomas (E and F), and squamous cell carcinomas positive for other HPVs (G–I) are shown. Specific signals are shown as brown staining (counterstained with hematoxylin, original magnification ×800; bars, 20 μm). High-grade squamous intraepithelial lesion (J), normal cervical epithelium (K and L), and experimental controls without primary antibody (M–O) are also shown.