Expression of BA transporters in the enterohepatic circulation.

<p>The mRNAs of proteins involved in BA transport in liver (uptake: Ntcp, Oatp1b2, and Oatp1a1; efflux: Bsep, Mrp2, and Mrp3) (A) and ileum (uptake: Asbt; intracellular transport: Ibabp; efflux: Ostα, Ostβ) (B) were quantified. Data are presented as means ± SEM of 5 mice. The triangle represents increased expression of Sirt1 in liver. # represents differences compared to WT mice, by one-way ANOVA, followed by Duncan’s post-hoc test (<i>p</i> < 0.05). * represents differences compared to AL mice of the same genotype by Student's <i>t</i>-test (<i>p</i> < 0.05).