Additional file 12: Figure S10. of CPAG: software for leveraging pleiotropy in GWAS to reveal similarity between human traits links plasma fatty acids and intestinal inflammation

Hierarchical clustering of NHGRI human traits based on Jaccard index. The hierarchical dendrogram and heat map of similarity for pairwise human traits were constructed based on the Jaccard similarity index, and significance of similarity was measured using a hypergeometric test implemented in the CPAG program. Only traits having at least one significant association (p < 0.05) against other traits are shown here. Colors in the heat map are based on the similarity index and scaled according to the color key. Colored blocks along the y-axis of the heat map and color of text for trait names are indicative of the nine assigned categories of traits. (PDF 75 kb