<p>For each SNP, results are given for the recessive (first number) and dominant part (second number). Results for inclusion probabilities are rounded to integers of percentage. Effect estimates are illustrated by the shade of grey as indicated. Results rounded to zero are omitted. Results for the lipid phenotypes LDL-C, HDL-C and TG are presented. TC is omitted due to high correlation with LDL-C.</p
See S1 Table 1a and 1b for detailed settings. Summary-level association statistics are simulated for...
<p>We present probabilities for inclusion of specified covariables and resulting effect sizes and co...
<p>Enrichment ratio is the ratio of the allele frequencies in the affected individuals (<i>n</i> = 2...
<p>Solid lines show mean (normalized) phenotype for each subfraction (see <a href="http://www.ploson...
<p>Genetic impacts on lipid level (β in <i>x</i>-axis) and CAD risk (OR in <i>y</i>-axis) are compar...
e relationships with the same genotype and the same lipid parameter in non-LG (P < 0.05 for each)...
<p>Estimates of odds ratio for the three lipid species ePC 38:5, PC 40:3 and PC 42:4, the reference ...
<p>All analyses are adjusted for age and sex.</p>a<p>according to Teslovich et al. <a href="http://w...
<p>Possible models of HDL-C, LDL-C, TG can contain up to 15 covariables (age, sex, BMI SDS, dominant...
Odds ratio per standard deviation increase in Q-Risk exposure phenotypes with respect to being class...
<p>Note that the effect of LDL modal density phenotype on LDL-P is rendered insignificant by HDL-C, ...
Traits are grouped based on their category and include: (A) body mass index (BMI) and body weight, (...
Previous Mendelian randomization studies have suggested that, while low-density lipoprotein choleste...
<p>LDL-P across LDL density phenotype adjusted for potentially confounding covariates.</p
<p>The univariate associations in column 2 are the phenotypes reported as being associated with each...
See S1 Table 1a and 1b for detailed settings. Summary-level association statistics are simulated for...
<p>We present probabilities for inclusion of specified covariables and resulting effect sizes and co...
<p>Enrichment ratio is the ratio of the allele frequencies in the affected individuals (<i>n</i> = 2...
<p>Solid lines show mean (normalized) phenotype for each subfraction (see <a href="http://www.ploson...
<p>Genetic impacts on lipid level (β in <i>x</i>-axis) and CAD risk (OR in <i>y</i>-axis) are compar...
e relationships with the same genotype and the same lipid parameter in non-LG (P < 0.05 for each)...
<p>Estimates of odds ratio for the three lipid species ePC 38:5, PC 40:3 and PC 42:4, the reference ...
<p>All analyses are adjusted for age and sex.</p>a<p>according to Teslovich et al. <a href="http://w...
<p>Possible models of HDL-C, LDL-C, TG can contain up to 15 covariables (age, sex, BMI SDS, dominant...
Odds ratio per standard deviation increase in Q-Risk exposure phenotypes with respect to being class...
<p>Note that the effect of LDL modal density phenotype on LDL-P is rendered insignificant by HDL-C, ...
Traits are grouped based on their category and include: (A) body mass index (BMI) and body weight, (...
Previous Mendelian randomization studies have suggested that, while low-density lipoprotein choleste...
<p>LDL-P across LDL density phenotype adjusted for potentially confounding covariates.</p
<p>The univariate associations in column 2 are the phenotypes reported as being associated with each...
See S1 Table 1a and 1b for detailed settings. Summary-level association statistics are simulated for...
<p>We present probabilities for inclusion of specified covariables and resulting effect sizes and co...
<p>Enrichment ratio is the ratio of the allele frequencies in the affected individuals (<i>n</i> = 2...