MicroRNAs- 31 and -200a are significantly downregulated in human retinoblastoma tumors and cell lines.

<p>(A) The expression level of miR-31 was measured in retinoblastomas as compared to normal pediatric retinas. (B) The expression level of miR-200a was measured in human retinoblastomas as compared to normal pediatric retinas. (C) The expression level of miR-31 and miR-200a was measured in human retinoblastoma cell lines (Y79, Weri1) as compared to normal pediatric retinas. Data represents mean and standard deviation from two independent experiments in triplicate. *denotes p< 0.05, ** denotes p< 0.003, *** denotes p<0.0005.