ARID1A regulates epithelial proliferation via modulating KLF15 expression with PGR (A) ChIP assay performed with uterine chromatin isolated <i>Arid1a</i>^<i>f/f</i> and <i>Arid1a</i>^<i>d/d</i> mice at 3.5 dpc using IgG, PGR, and ARID1A antibodies followed by qPCR.

<p>The results represent the mean ± SEM. **, <i>p</i> < 0.01. (B) Protein interaction between ARID1A and PGR was examined by immunoprecipitation and transient transfection in Ishikawa cells. (C) Immunohistochemical analysis of KLF4 and KLF15 were performed on uteri of <i>Arid1a</i>^<i>f/f</i> (a and b) and <i>Arid1a</i>^<i>d/d</i> (c and d) mice at 3.5 dpc. (D) The immunohistochemical histological score (H-score) of KLF4 and KLF15 proteins (n = 21 per group at secretory phase). The results represent the mean ± SEM. *** <i>p</i><0.001. (E) The level of KLF4 and KLF15 in human endometrium without (a and b) and with (c and d) endometriosis were performed by immunohistochemical analysis.