Additional file 5: Table S8. of The senescent methylome and its relationship with cancer, ageing and germline genetic variation in humans

Additional file 8: Table S1. of Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome

Warren Cheung (83908)
Xiaojian Shao (3465695)
Andréanne Morin (3499337)
Valérie Siroux (271568)
Tony Kwan (232656)
Bing Ge (42609)
Dylan Aïssi (635733)
Lu Chen (75170)
Louella Vasquez (3830902)
Fiona Allum (3465704)
Frédéric Guénard (684715)
Emmanuelle Bouzigon (166245)
Marie-Michelle Simon (3465701)
Elodie Boulier (3830896)
Adriana Redensek (3830905)
Stephen Watt (377395)
Avik Datta (3830908)
Laura Clarke (2190)
Paul Flicek (77154)
Daniel Mead (3507788)
Dirk Paul (3428945)
Stephan Beck (5246)
Guillaume Bourque (123960)
Mark Lathrop (17971)
André Tchernof (541752)
Marie-Claude Vohl (684717)
Florence Demenais (73668)
Isabelle Pin (166259)
Kate Downes (242215)
Hendrick Stunnenberg (3830899)
Nicole Soranzo (12361)
Tomi Pastinen (15737)
Elin Grundberg (116416)

March 2017

This file details for each cell type mean fold coverage (for CpG methylation sequencing) and total a...

Additional file 2: of DNA methylome profiling of all-cause mortality in comparison with age-associated methylation patterns

Jesper Beltoft Lund (6318251)
Shuxia Li (849726)
Jan Baumbach (14867)
Anne Svane (6318254)
Jacob Hjelmborg (184895)
Lene Christiansen (158189)
Kaare Christensen (75575)
Paul Redmond (107693)
Riccardo Marioni (669892)
Ian Deary (489588)
Qihua Tan (92926)

February 2019

Table S1 List of significant CpGs (FDRâ<â0.05) found using the Cox-proportional hazard model for...

MOESM1 of Methylome of human senescent hematopoietic progenitors

Stephen Capone (1756927)
Anthony Colombo (5269589)
Benjamin Johnson (1872937)
Tim Triche (6113672)
Giridharan Ramsingh (5269601)

December 2018

Additional file 1. Compiled list of differentially methylated regions in senescent vs. active HSPCs,...

Additional file 2: Table S1. of The senescent methylome and its relationship with cancer, ageing and germline genetic variation in humans

Robert Lowe (724766)
Marita Overhoff (3566255)
Sreeram Ramagopalan (3253560)
James Garbe (3566252)
James Koh (3045738)
Martha Stampfer (279112)
David Beach (3566249)
Vardhman Rakyan (3191682)
Cleo Bishop (3566258)

September 2015

Table containing the annotated information of the 969 experiment 1 only senDMPs. (CSV 290 kb

Additional file 4: Table S3. of The senescent methylome and its relationship with cancer, ageing and germline genetic variation in humans

Robert Lowe (724766)
Marita Overhoff (3566255)
Sreeram Ramagopalan (3253560)
James Garbe (3566252)
James Koh (3045738)
Martha Stampfer (279112)
David Beach (3566249)
Vardhman Rakyan (3191682)
Cleo Bishop (3566258)

September 2015

Table containing the annotated information of the 725 agree senDMPs. (CSV 244 kb

Additional file 9: Table S4. of The senescent methylome and its relationship with cancer, ageing and germline genetic variation in humans

Robert Lowe (724766)
Marita Overhoff (3566255)
Sreeram Ramagopalan (3253560)
James Garbe (3566252)
James Koh (3045738)
Martha Stampfer (279112)
David Beach (3566249)
Vardhman Rakyan (3191682)
Cleo Bishop (3566258)

September 2015

Table containing the annotated information of the senescence associated probes reaching 0.01 FDR and...

Additional file 4: Table S5. of Aging-associated DNA methylation changes in middle-aged individuals: the Young Finns study

L. Kananen (3495239)
S. Marttila (3495242)
T. Nevalainen (3495245)
J. Jylhävä (3495248)
N. Mononen (3495254)
M. Kähönen (3495260)
O. Raitakari (3495236)
T. Lehtimäki (3495257)
M. Hurme (3495251)

February 2016

A summary table where the 70 genes with more than one hypomethylated or more than one hypermethylate...

Additional file 5: Table S14. of DNA methylation patterns associated with oxidative stress in an ageing population

Ăsa Hedman (3486284)
Mihkel Zilmer (673181)
Johan SundstrĂśm (3486287)
Lars Lind (88400)
Erik Ingelsson (232651)

November 2016

Nominal significant associations (p-value <0.05) for significant meQTL SNPs in GWAS data from the CA...

Additional file 1: Figure S1. of The senescent methylome and its relationship with cancer, ageing and germline genetic variation in humans

Robert Lowe (724766)
Marita Overhoff (3566255)
Sreeram Ramagopalan (3253560)
James Garbe (3566252)
James Koh (3045738)
Martha Stampfer (279112)
David Beach (3566249)
Vardhman Rakyan (3191682)
Cleo Bishop (3566258)

September 2015

Model of senescence barriers in cultured HMECs. Figure S2. Morphology of DS cells following transfec...

Additional file 5: of Novel regional age-associated DNA methylation changes within human common disease-associated loci

Christopher Bell (129582)
Yudong Xia (3417977)
Wei Yuan (64653)
Fei Gao (29262)
Kirsten Ward (3417971)
Leonie Roos (3417974)
Massimo Mangino (87550)
Pirro Hysi (247490)
Jordana Bell (667256)
Jun Wang (5906)
Timothy Spector (348486)

September 2016

Figure S3. Genotype-interaction analysis. Variation in ageing signal depending on genotype. Homozygo...

Additional file 5: of DNA methylome profiling of all-cause mortality in comparison with age-associated methylation patterns

Jesper Beltoft Lund (6318251)
Shuxia Li (849726)
Jan Baumbach (14867)
Anne Svane (6318254)
Jacob Hjelmborg (184895)
Lene Christiansen (158189)
Kaare Christensen (75575)
Paul Redmond (107693)
Riccardo Marioni (669892)
Ian Deary (489588)
Qihua Tan (92926)

February 2019

Table S2 List of pathways enriched by negative mortality association CpGs with FDRâ<â0.05. (XLSX...

Additional file 5: of Genotype effects contribute to variation in longitudinal methylome patterns in older people

Qian Zhang (49333)
Riccardo Marioni (669892)
Matthew Robinson (253933)
Jon Higham (5880614)
Duncan Sproul (3186)
Naomi Wray (3449882)
Ian Deary (489588)
Allan McRae (3400103)
Peter Visscher (3400094)

October 2018

Table S4. Pathway analysis on the genes around the 1507 rsCpGs in ConsensusPathDB database. (CSV 16Â...

Additional file 5: of Normal breast tissue DNA methylation differences at regulatory elements are associated with the cancer risk factor age

Kevin Johnson (684369)
E. Houseman (3398849)
Jessica King (430832)
Brock Christensen (3472082)

July 2017

Age-related DNA methylation in the human normal breast validated in adjacent-to-tumor normal breast ...

Additional file 3: of Genotype effects contribute to variation in longitudinal methylome patterns in older people

Qian Zhang (49333)
Riccardo Marioni (669892)
Matthew Robinson (253933)
Jon Higham (5880614)
Duncan Sproul (3186)
Naomi Wray (3449882)
Ian Deary (489588)
Allan McRae (3400103)
Peter Visscher (3400094)

October 2018

Table S2. Probes with a significant random slope in two groups of different individuals. Probe id, c...

Additional file 4: of Genotype effects contribute to variation in longitudinal methylome patterns in older people

Qian Zhang (49333)
Riccardo Marioni (669892)
Matthew Robinson (253933)
Jon Higham (5880614)
Duncan Sproul (3186)
Naomi Wray (3449882)
Ian Deary (489588)
Allan McRae (3400103)
Peter Visscher (3400094)

October 2018

Table S3. Gene Ontology analysis on the genes around the 1507 rsCpGs. (CSV 3Â kb

Additional file 8: Table S1. of Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome

Warren Cheung (83908)
Xiaojian Shao (3465695)
Andréanne Morin (3499337)
Valérie Siroux (271568)
Tony Kwan (232656)
Bing Ge (42609)
Dylan Aïssi (635733)
Lu Chen (75170)
Louella Vasquez (3830902)
Fiona Allum (3465704)
Frédéric Guénard (684715)
Emmanuelle Bouzigon (166245)
Marie-Michelle Simon (3465701)
Elodie Boulier (3830896)
Adriana Redensek (3830905)
Stephen Watt (377395)
Avik Datta (3830908)
Laura Clarke (2190)
Paul Flicek (77154)
Daniel Mead (3507788)
Dirk Paul (3428945)
Stephan Beck (5246)
Guillaume Bourque (123960)
Mark Lathrop (17971)
André Tchernof (541752)
Marie-Claude Vohl (684717)
Florence Demenais (73668)
Isabelle Pin (166259)
Kate Downes (242215)
Hendrick Stunnenberg (3830899)
Nicole Soranzo (12361)
Tomi Pastinen (15737)
Elin Grundberg (116416)

March 2017

This file details for each cell type mean fold coverage (for CpG methylation sequencing) and total a...

Additional file 2: of DNA methylome profiling of all-cause mortality in comparison with age-associated methylation patterns

Jesper Beltoft Lund (6318251)
Shuxia Li (849726)
Jan Baumbach (14867)
Anne Svane (6318254)
Jacob Hjelmborg (184895)
Lene Christiansen (158189)
Kaare Christensen (75575)
Paul Redmond (107693)
Riccardo Marioni (669892)
Ian Deary (489588)
Qihua Tan (92926)

February 2019

Table S1 List of significant CpGs (FDRâ<â0.05) found using the Cox-proportional hazard model for...

MOESM1 of Methylome of human senescent hematopoietic progenitors

Stephen Capone (1756927)
Anthony Colombo (5269589)
Benjamin Johnson (1872937)
Tim Triche (6113672)
Giridharan Ramsingh (5269601)

December 2018

Additional file 1. Compiled list of differentially methylated regions in senescent vs. active HSPCs,...

Additional file 2: Table S1. of The senescent methylome and its relationship with cancer, ageing and germline genetic variation in humans

Robert Lowe (724766)
Marita Overhoff (3566255)
Sreeram Ramagopalan (3253560)
James Garbe (3566252)
James Koh (3045738)
Martha Stampfer (279112)
David Beach (3566249)
Vardhman Rakyan (3191682)
Cleo Bishop (3566258)

September 2015

Table containing the annotated information of the 969 experiment 1 only senDMPs. (CSV 290 kb

Additional file 4: Table S3. of The senescent methylome and its relationship with cancer, ageing and germline genetic variation in humans

Robert Lowe (724766)
Marita Overhoff (3566255)
Sreeram Ramagopalan (3253560)
James Garbe (3566252)
James Koh (3045738)
Martha Stampfer (279112)
David Beach (3566249)
Vardhman Rakyan (3191682)
Cleo Bishop (3566258)

September 2015

Table containing the annotated information of the 725 agree senDMPs. (CSV 244 kb

Additional file 9: Table S4. of The senescent methylome and its relationship with cancer, ageing and germline genetic variation in humans

Robert Lowe (724766)
Marita Overhoff (3566255)
Sreeram Ramagopalan (3253560)
James Garbe (3566252)
James Koh (3045738)
Martha Stampfer (279112)
David Beach (3566249)
Vardhman Rakyan (3191682)
Cleo Bishop (3566258)

September 2015

Table containing the annotated information of the senescence associated probes reaching 0.01 FDR and...

Additional file 4: Table S5. of Aging-associated DNA methylation changes in middle-aged individuals: the Young Finns study

L. Kananen (3495239)
S. Marttila (3495242)
T. Nevalainen (3495245)
J. Jylhävä (3495248)
N. Mononen (3495254)
M. Kähönen (3495260)
O. Raitakari (3495236)
T. Lehtimäki (3495257)
M. Hurme (3495251)

February 2016

A summary table where the 70 genes with more than one hypomethylated or more than one hypermethylate...

Additional file 5: Table S14. of DNA methylation patterns associated with oxidative stress in an ageing population

Ăsa Hedman (3486284)
Mihkel Zilmer (673181)
Johan SundstrĂśm (3486287)
Lars Lind (88400)
Erik Ingelsson (232651)

November 2016

Nominal significant associations (p-value <0.05) for significant meQTL SNPs in GWAS data from the CA...

Additional file 1: Figure S1. of The senescent methylome and its relationship with cancer, ageing and germline genetic variation in humans

Robert Lowe (724766)
Marita Overhoff (3566255)
Sreeram Ramagopalan (3253560)
James Garbe (3566252)
James Koh (3045738)
Martha Stampfer (279112)
David Beach (3566249)
Vardhman Rakyan (3191682)
Cleo Bishop (3566258)

September 2015

Model of senescence barriers in cultured HMECs. Figure S2. Morphology of DS cells following transfec...

Additional file 5: of Novel regional age-associated DNA methylation changes within human common disease-associated loci

Christopher Bell (129582)
Yudong Xia (3417977)
Wei Yuan (64653)
Fei Gao (29262)
Kirsten Ward (3417971)
Leonie Roos (3417974)
Massimo Mangino (87550)
Pirro Hysi (247490)
Jordana Bell (667256)
Jun Wang (5906)
Timothy Spector (348486)

September 2016

Figure S3. Genotype-interaction analysis. Variation in ageing signal depending on genotype. Homozygo...

Additional file 5: of DNA methylome profiling of all-cause mortality in comparison with age-associated methylation patterns

Jesper Beltoft Lund (6318251)
Shuxia Li (849726)
Jan Baumbach (14867)
Anne Svane (6318254)
Jacob Hjelmborg (184895)
Lene Christiansen (158189)
Kaare Christensen (75575)
Paul Redmond (107693)
Riccardo Marioni (669892)
Ian Deary (489588)
Qihua Tan (92926)

February 2019

Table S2 List of pathways enriched by negative mortality association CpGs with FDRâ<â0.05. (XLSX...

Additional file 5: of Genotype effects contribute to variation in longitudinal methylome patterns in older people

Qian Zhang (49333)
Riccardo Marioni (669892)
Matthew Robinson (253933)
Jon Higham (5880614)
Duncan Sproul (3186)
Naomi Wray (3449882)
Ian Deary (489588)
Allan McRae (3400103)
Peter Visscher (3400094)

October 2018

Table S4. Pathway analysis on the genes around the 1507 rsCpGs in ConsensusPathDB database. (CSV 16Â...

Additional file 5: of Normal breast tissue DNA methylation differences at regulatory elements are associated with the cancer risk factor age

Kevin Johnson (684369)
E. Houseman (3398849)
Jessica King (430832)
Brock Christensen (3472082)

July 2017

Age-related DNA methylation in the human normal breast validated in adjacent-to-tumor normal breast ...

Additional file 3: of Genotype effects contribute to variation in longitudinal methylome patterns in older people

Qian Zhang (49333)
Riccardo Marioni (669892)
Matthew Robinson (253933)
Jon Higham (5880614)
Duncan Sproul (3186)
Naomi Wray (3449882)
Ian Deary (489588)
Allan McRae (3400103)
Peter Visscher (3400094)

October 2018

Table S2. Probes with a significant random slope in two groups of different individuals. Probe id, c...

Additional file 4: of Genotype effects contribute to variation in longitudinal methylome patterns in older people

Qian Zhang (49333)
Riccardo Marioni (669892)
Matthew Robinson (253933)
Jon Higham (5880614)
Duncan Sproul (3186)
Naomi Wray (3449882)
Ian Deary (489588)
Allan McRae (3400103)
Peter Visscher (3400094)

October 2018

Table S3. Gene Ontology analysis on the genes around the 1507 rsCpGs. (CSV 3Â kb

Additional file 8: Table S1. of Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome

Warren Cheung (83908)
Xiaojian Shao (3465695)
Andréanne Morin (3499337)
Valérie Siroux (271568)
Tony Kwan (232656)
Bing Ge (42609)
Dylan Aïssi (635733)
Lu Chen (75170)
Louella Vasquez (3830902)
Fiona Allum (3465704)
Frédéric Guénard (684715)
Emmanuelle Bouzigon (166245)
Marie-Michelle Simon (3465701)
Elodie Boulier (3830896)
Adriana Redensek (3830905)
Stephen Watt (377395)
Avik Datta (3830908)
Laura Clarke (2190)
Paul Flicek (77154)
Daniel Mead (3507788)
Dirk Paul (3428945)
Stephan Beck (5246)
Guillaume Bourque (123960)
Mark Lathrop (17971)
André Tchernof (541752)
Marie-Claude Vohl (684717)
Florence Demenais (73668)
Isabelle Pin (166259)
Kate Downes (242215)
Hendrick Stunnenberg (3830899)
Nicole Soranzo (12361)
Tomi Pastinen (15737)
Elin Grundberg (116416)

March 2017

This file details for each cell type mean fold coverage (for CpG methylation sequencing) and total a...

Additional file 2: of DNA methylome profiling of all-cause mortality in comparison with age-associated methylation patterns

Jesper Beltoft Lund (6318251)
Shuxia Li (849726)
Jan Baumbach (14867)
Anne Svane (6318254)
Jacob Hjelmborg (184895)
Lene Christiansen (158189)
Kaare Christensen (75575)
Paul Redmond (107693)
Riccardo Marioni (669892)
Ian Deary (489588)
Qihua Tan (92926)

February 2019

Table S1 List of significant CpGs (FDRâ<â0.05) found using the Cox-proportional hazard model for...

MOESM1 of Methylome of human senescent hematopoietic progenitors

Stephen Capone (1756927)
Anthony Colombo (5269589)
Benjamin Johnson (1872937)
Tim Triche (6113672)
Giridharan Ramsingh (5269601)

December 2018

Additional file 1. Compiled list of differentially methylated regions in senescent vs. active HSPCs,...

Additional file 5: Table S8. of The senescent methylome and its relationship with cancer, ageing and germline genetic variation in humans

Abstract

Extracted data

Additional file 5: Table S8. of The senescent methylome and its relationship with cancer, ageing and germline genetic variation in humans

Abstract

Extracted data

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