Comparisons analysis of primary tumors and cell lines. oaCGH data from primary tumors and cell lines were simultaneously analyzed and compared using the Comparisons algorithm (Nexus Copy Number, Biodiscovery). Few aberrant regions were evident in only the primary tumors or the cell lines without being present in the other. (XLSX 9Â kb
Table S4. Top 500 upstream regulators of differentially expressed genes in canine iUC. Predicted act...
IC75 values of the isolated human (A375 and Sk-Mel28) and canine melanoma (Ocr_OCMM1X and Ocr_OCMM2X...
Figure S1. Representative images of isolated canine fibroblasts with an extended cellular life span ...
Clustered heat map of cell line differential expression. Unsupervised hierarchical clustering of gen...
Table S1. Sequences of the oligonucleotide primers used for quantitative PCR. (XLSX 11 kb
Comparative analysis in CGH profiles of canine chromosomes 11, 22, 26 and 30 in Dog_2 vs. Dog_1 deri...
Comparative analysis in CGH profiles of canine chromosomes 11, 22, 26 and 30 in Dog_2 vs. Dog_1 deri...
CGH profiles of canine chromosomes 11, 22, 26 and 30 in Dog_1. Comparative analysis between the prim...
Figure S1. Principal component analysis (PCA) plot of canine iUC with or without BRAF V595E mutation...
Table S2. Top 500 upregulated differentially expressed genes (DEGs) in canine iUC. (XLSX 26 kb
CGH profiles of canine chromosomes 11, 22, 26 and 30 in Dog_2. Comparative analysis between the prim...
Table S3. Top 500 downregulated differentially expressed genes (DEGs) in canine iUC. (XLSX 25 kb
Figure S3. mRNA expression of top 5 DEGs in the bladder of healthy dogs and dogs with iUC. TBP was u...
Summary of antibodies used for immunohistochemical and Western Blot analysis in the study. (TIF 77 k...
Immunohistochemical analysis of Dog_1 (A, C) and Dog_2 (B, D) engrafted tumors using Hematoxilin & E...
Table S4. Top 500 upstream regulators of differentially expressed genes in canine iUC. Predicted act...
IC75 values of the isolated human (A375 and Sk-Mel28) and canine melanoma (Ocr_OCMM1X and Ocr_OCMM2X...
Figure S1. Representative images of isolated canine fibroblasts with an extended cellular life span ...
Clustered heat map of cell line differential expression. Unsupervised hierarchical clustering of gen...
Table S1. Sequences of the oligonucleotide primers used for quantitative PCR. (XLSX 11 kb
Comparative analysis in CGH profiles of canine chromosomes 11, 22, 26 and 30 in Dog_2 vs. Dog_1 deri...
Comparative analysis in CGH profiles of canine chromosomes 11, 22, 26 and 30 in Dog_2 vs. Dog_1 deri...
CGH profiles of canine chromosomes 11, 22, 26 and 30 in Dog_1. Comparative analysis between the prim...
Figure S1. Principal component analysis (PCA) plot of canine iUC with or without BRAF V595E mutation...
Table S2. Top 500 upregulated differentially expressed genes (DEGs) in canine iUC. (XLSX 26 kb
CGH profiles of canine chromosomes 11, 22, 26 and 30 in Dog_2. Comparative analysis between the prim...
Table S3. Top 500 downregulated differentially expressed genes (DEGs) in canine iUC. (XLSX 25 kb
Figure S3. mRNA expression of top 5 DEGs in the bladder of healthy dogs and dogs with iUC. TBP was u...
Summary of antibodies used for immunohistochemical and Western Blot analysis in the study. (TIF 77 k...
Immunohistochemical analysis of Dog_1 (A, C) and Dog_2 (B, D) engrafted tumors using Hematoxilin & E...
Table S4. Top 500 upstream regulators of differentially expressed genes in canine iUC. Predicted act...
IC75 values of the isolated human (A375 and Sk-Mel28) and canine melanoma (Ocr_OCMM1X and Ocr_OCMM2X...
Figure S1. Representative images of isolated canine fibroblasts with an extended cellular life span ...