Measurement of <i>I</i><sub>f</sub> currents in mESC-CMs.
- Yukihiro Saito (797587)
- Kazufumi Nakamura (336712)
- Masashi Yoshida (227874)
- Hiroki Sugiyama (351211)
- Tohru Ohe (351219)
- Junko Kurokawa (253979)
- Tetsushi Furukawa (253981)
- Makoto Takano (371653)
- Satoshi Nagase (351216)
- Hiroshi Morita (124362)
- Kengo F. Kusano (797588)
- Hiroshi Ito (297745)
Publication date
September 2015
DOIAbstract
<p>A. Representative <i>I</i><sub>f</sub> currents in <i>EGFP</i>-(left) or <i>Hcn4/EGFP-</i>(right) overexpressing mESC-CMs. HCN4-overexpressing mESC-CMs showed a larger <i>I</i><sub>f</sub> current than did non-overexpressing cells. <i>I</i><sub>f</sub> currents through activated HCN channels were obtained during hyperpolarizing test pulses of 5 seconds between -45 and -125 mV in 20 mV increments from a holding potential of -35 mV. B. <i>I</i><sub>f</sub>-V relationship curve in <i>EGFP</i>-(blue line) or <i>Hcn4/EGFP-</i>(red line) overexpressing mESC-CMs.</p
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