Serum cytokine levels, PCA and cross validated probabilities in training set.

<p><b>A.</b> Heat map of supervised one-way hierarchical clustering of 18 PAM-identified cytokines in normal and GBM sera of the training set. A dual-color code was used, with red and green indicating high and low abundance, respectively. The white line separates normal from GBM samples. <b>B.</b> PCA was performed using serum levels of 18 PAM-identified cytokines of normal and GBM sera in the training set. A scatter plot was generated using first three principal components for each sample. The color code of the samples is as indicated. <b>C.</b> The graph shows detailed probabilities of 10-fold cross-validation for the samples of training set based on the serum levels of 18 PAM-identified cytokines. The probability of a given sample as normal (green color) and GBM (red color) are shown. This was predicted by the PAM program, based on which type of sample (normal <i>vs</i>. GBM) probability is higher. The original histological type of the samples is indicated above the graph.