<p>Respiration rates corrected for wet mass (A) and citrate synthase activity (B); oxidative phosphorylation coupling efficiency (OCE) as a marker of mitochondrial coupling (C); and ratio between octanoyl carnitine- and pyruvate-supported respiration (FAO) as a marker of preference for fatty acid oxidation (D) after normoxia (N, white), short-term hypoxia (H2, light blue) or sustained hypoxia (H14, dark blue). * <i>p</i> ≤ 0.05, ** <i>p</i> ≤ 0.01 vs. normoxia; † <i>p</i> ≤ 0.05 vs. short-term hypoxia. Data represent mean ± SEM.</p
Although the heart has been considered pri-marily an aerobic organ, recent work (1) has re-emphasize...
<p>Renal and hepatic complex 1-dependent state 2, 3 and 4 mitochondrial respiration using glutamate ...
Increased mechanical stress and contractility characterizes normal left ventricular (LV) subendocard...
<p>Respiration rates corrected for wet mass (A) and citrate synthase activity (B); oxidative phospho...
<p>mRNA levels of <i>Ppara</i> and its targets (A); activity of citrate synthase (CS), 3-hydroxyacyl...
<p>O<sub>2</sub>-consumption of permeabilized BK<sup>+/+</sup> fibres (blue bars) and fibres isolate...
The capacity of mitochondria to respond to changes in oxygen delivery has the potential to affect th...
<p>ADP-stimulated (<i>state 3</i>) and resting (<i>state 4</i>) respiration rates are shown for mito...
AbstractObjectives: Mitochondrial abnormalities have been described in cardiac tissue of patients wi...
<p>(A) Mitochondrial respiration was measured in saponin-permeabilized cardiac fibers from HSPB2wt (...
Hypoxia is a consequence of cardiac disease and downregulates mitochondrial metabolism, yet the mole...
Oxygen consumption rates (OCR) of isolated mitochondria from livers after 2, 4 and 8 weeks of high-f...
The effects of environmental hypoxia on cardiac and skeletal muscle metabolism are dependent on the ...
OBJECTIVE: Increased mechanical stress and contractility characterizes normal left ventricular (LV) ...
Chronic hypoxia decreases cardiomyocyte respiration, yet the mitochondrial mechanisms remain largely...
Although the heart has been considered pri-marily an aerobic organ, recent work (1) has re-emphasize...
<p>Renal and hepatic complex 1-dependent state 2, 3 and 4 mitochondrial respiration using glutamate ...
Increased mechanical stress and contractility characterizes normal left ventricular (LV) subendocard...
<p>Respiration rates corrected for wet mass (A) and citrate synthase activity (B); oxidative phospho...
<p>mRNA levels of <i>Ppara</i> and its targets (A); activity of citrate synthase (CS), 3-hydroxyacyl...
<p>O<sub>2</sub>-consumption of permeabilized BK<sup>+/+</sup> fibres (blue bars) and fibres isolate...
The capacity of mitochondria to respond to changes in oxygen delivery has the potential to affect th...
<p>ADP-stimulated (<i>state 3</i>) and resting (<i>state 4</i>) respiration rates are shown for mito...
AbstractObjectives: Mitochondrial abnormalities have been described in cardiac tissue of patients wi...
<p>(A) Mitochondrial respiration was measured in saponin-permeabilized cardiac fibers from HSPB2wt (...
Hypoxia is a consequence of cardiac disease and downregulates mitochondrial metabolism, yet the mole...
Oxygen consumption rates (OCR) of isolated mitochondria from livers after 2, 4 and 8 weeks of high-f...
The effects of environmental hypoxia on cardiac and skeletal muscle metabolism are dependent on the ...
OBJECTIVE: Increased mechanical stress and contractility characterizes normal left ventricular (LV) ...
Chronic hypoxia decreases cardiomyocyte respiration, yet the mitochondrial mechanisms remain largely...
Although the heart has been considered pri-marily an aerobic organ, recent work (1) has re-emphasize...
<p>Renal and hepatic complex 1-dependent state 2, 3 and 4 mitochondrial respiration using glutamate ...
Increased mechanical stress and contractility characterizes normal left ventricular (LV) subendocard...