Regulation of metabolism in the left ventricle.

<p>mRNA levels of <i>Ppara</i> and its targets (A); activity of citrate synthase (CS), 3-hydroxyacyl dehydrogenase (HADH), hexokinase (HK) and lactate dehydrogenase (LDH) (B); and levels of UCP3 and protein carbonyls (C) after normoxia (N, white), short-term hypoxia (H2, light blue) or sustained hypoxia (H14, dark blue). * <i>p</i> ≤ 0.05, ** <i>p</i> ≤ 0.01 <i>vs</i>. normoxia; † <i>p</i> ≤ 0.05 <i>vs</i>. short-term hypoxia. Data represent mean ± SEM.